Protein Alignment UBQLN2 and Ubqln2

DIOPT Version :8

• Sequence 1: NP_038472.2
• Gene: UBQLN2 / 29978
• HGNCID: 12509
• Length: 624
• Species: Homo sapiens
• Sequence 2: NP_061268.2
• Gene: Ubqln2 / 54609
• MGIID: 1860283
• Length: 638
• Species: Mus musculus
• Alignment Length: 641
• Identity: 559/642 (87%)
• Similarity: 597/642 (93%)
• Gaps: 20/642 (3%)

Human     1 MAENGESSGPPRPSRGPAAAQGSAAAPAEPKIIKVTVKTPKEKEEFAVPENSSVQQFKEAISKRF 65
            ||||||||||||||||||||.|:|:.||||||||||||||||||||||||||:||||||||||||
Mouse     1 MAENGESSGPPRPSRGPAAAPGAASPPAEPKIIKVTVKTPKEKEEFAVPENSTVQQFKEAISKRF 65

Human    66 KSQTDQLVLIFAGKILKDQDTLIQHGIHDGLTVHLVIKSQNRPQGQ-STQPSNAAGTNTTSAST- 128
            ||||||||||||||||||||||:||||||||||||||||||||||| :||||..|||:||:.:|
Mouse    66 KSQTDQLVLIFAGKILKDQDTLMQHGIHDGLTVHLVIKSQNRPQGQATTQPSTTAGTSTTTTTTT 130

Human   129 ------------PRSNSTPISTNSNPFGLGSLGGLAGLSSLGLSSTNFSELQSQMQQQLMASPEM 181
                        |||:|||.:|||:.|||||   |:.||:|||:|.||:|||:||||||:|||||
Mouse   131 TAAAPAATTSSAPRSSSTPTTTNSSSFGLGS---LSSLSNLGLNSPNFTELQNQMQQQLLASPEM 192

Human   182 MIQIMENPFVQSMLSNPDLMRQLIMANPQMQQLIQRNPEISHLLNNPDIMRQTLEIARNPAMMQE 246
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Mouse   193 MIQIMENPFVQSMLSNPDLMRQLIMANPQMQQLIQRNPEISHLLNNPDIMRQTLEIARNPAMMQE 257

Human   247 MMRNQDLALSNLESIPGGYNALRRMYTDIQEPMLNAAQEQFGGNPFASVGSSSSSGEGTQPSRTE 311
            |||||||||||||||||||||||||||||||||||||||||||||||:|||||:|||||||||||
Mouse   258 MMRNQDLALSNLESIPGGYNALRRMYTDIQEPMLNAAQEQFGGNPFATVGSSSTSGEGTQPSRTE 322

Human   312 NRDPLPNPWAPPPATQSSATTSTTTST--GSGSGNSSSNAT-GNTVAAANYVASIFSTPGMQSLL 373
            |||||||||||||.||::|||:|||:|  |||||:|||:.| |||:|||||||||||||||||||
Mouse   323 NRDPLPNPWAPPPTTQTAATTTTTTTTSSGSGSGSSSSSTTAGNTMAAANYVASIFSTPGMQSLL 387

Human   374 QQITENPQLIQNMLSAPYMRSMMQSLSQNPDLAAQMMLNSPLFTANPQLQEQMRPQLPAFLQQMQ 438
            |||||||||||||||||||||||||||||||:||||||:|||||:|||||||||||||.||||||
Mouse   388 QQITENPQLIQNMLSAPYMRSMMQSLSQNPDMAAQMMLSSPLFTSNPQLQEQMRPQLPNFLQQMQ 452

Human   439 NPDTLSAMSNPRAMQALMQIQQGLQTLATEAPGLIPSFTPGVGVGVLGTAIGPVGPVTPIGPIGP 503
            ||:|::||||||||||||||||||||||||||||||||.||||:|||||||.|||||||||||||
Mouse   453 NPETIAAMSNPRAMQALMQIQQGLQTLATEAPGLIPSFAPGVGMGVLGTAITPVGPVTPIGPIGP 517

Human   504 IVPFTPIGPIGPIGPTGPAAPPGSTGSGGPTGPTVSSAAPSETTSPTSESGPNQQFIQQMVQALA 568
            |||||||||||||||||||:.|||||:|.|...||||:||:||.||||||||||||||||||||.
Mouse   518 IVPFTPIGPIGPIGPTGPASSPGSTGTGIPPATTVSSSAPTETISPTSESGPNQQFIQQMVQALT 582

Human   569 GANAPQLPNPEVRFQQQLEQLNAMGFLNREANLQALIATGGDINAAIERLLGSQPS 624
            |.:.||.|||||||||||||||||||||||||||||||||||||||||||||||||
Mouse   583 GGSPPQPPNPEVRFQQQLEQLNAMGFLNREANLQALIATGGDINAAIERLLGSQPS 638

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
UBQLN2	NP_038472.2	UBQ	33..103	CDD:214563	68/70 (97%)
		hPLIC_N	33..103	CDD:176403	68/70 (97%)
		STI1	382..426	CDD:128966	41/44 (93%)
		12 X 3 AA tandem repeats of P-X-X	491..526		33/35 (94%)
		UBA_PLICs	581..620	CDD:270582	39/39 (100%)
Ubqln2	NP_061268.2	UBQ	33..103	CDD:214563	68/70 (97%)
		hPLIC_N	33..103	CDD:176403	68/70 (97%)
		STI1	396..440	CDD:128966	41/44 (93%)
		11 X 3 AA tandem repeats P-X-X	505..537		32/32 (100%)
		UBA_PLICs	595..634	CDD:270582	39/39 (100%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930				C156734489
eggNOG	1	0.900				E1_COG5272
HGNC	1	1.500
Hieranoid	1	1.000
Homologene	1	1.000				H81830
Inparanoid	1	1.050	1085	1.000	Inparanoid score	I5018
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010
OrthoDB	1	1.010				D116115at9347
OrthoFinder	1	1.000				FOG0000468
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900				OOG5_127163
Panther	1	1.100			LDO	PTHR10677
Phylome	1	0.910		0.800	Consistency score
RoundUp	0	0.000	Not matched by this tool.
TreeFam	1	0.960
	13	13.270