Protein Alignment UBQLN2 and ubqln1

DIOPT Version :10

• Sequence 1: NP_038472.2
• Gene: UBQLN2 / 29978
• HGNCID: 12509
• Length: 624
• Species: Homo sapiens
• Sequence 2: NP_989221.1
• Gene: ubqln1 / 394829
• XenbaseID: XB-GENE-986025
• Length: 564
• Species: Xenopus tropicalis
• Alignment Length: 612
• Identity: 426/612 - (69%)
• Similarity: 491/612 - (80%)
• Gaps: 56/612 - (9%)

Human    17 PAAAQGSAAAPAEPKIIKVTVKTPKEKEEFAVPENSSVQQFKEAISKRFKSQTDQLVLIFAGKIL 81
            |:::..|::.||  :||||||||||||||||||||||:::|||.|||||||.|:|||||||||||
 Frog     5 PSSSTPSSSDPA--RIIKVTVKTPKEKEEFAVPENSSIREFKEDISKRFKSSTEQLVLIFAGKIL 67

Human    82 KDQDTLIQHGIHDGLTVHLVIKSQNRPQGQSTQPSNAAGTNTTSASTPRSNSTPISTNSNPFGLG 146
            ||||||.|||||||||||||||:|||.|..:...::::.|:.|:::|..|::|..:|...|.|||
 Frog    68 KDQDTLSQHGIHDGLTVHLVIKTQNRSQAATASQASSSSTSATNSTTSSSSTTTTTTTGTPLGLG 132

Human   147 SLGGLAGLSSLGLSSTNFSELQSQMQQQLMASPEMMIQIMENPFVQSMLSNPDLMRQLIMANPQM 211
            .|||||||||||::::||||||||||||||::||||:||||||||||||||||||.|||||||||
 Frog   133 GLGGLAGLSSLGMNASNFSELQSQMQQQLMSNPEMMVQIMENPFVQSMLSNPDLMSQLIMANPQM 197

Human   212 QQLIQRNPEISHLLNNPDIMRQTLEIARNPAMMQEMMRNQDLALSNLESIPGGYNALRRMYTDIQ 276
            ||||||||||||:||||||||||||:|||||||||||||||.|||||||||||||||||||||||
 Frog   198 QQLIQRNPEISHMLNNPDIMRQTLELARNPAMMQEMMRNQDRALSNLESIPGGYNALRRMYTDIQ 262

Human   277 EPMLNAAQEQFGGNPFASVGSSSSSGEGTQPSRTENRDPLPNPWAPPPATQSSATTSTTTSTGSG 341
            ||||||||||||||||||:.|::|:. |.||||||||||||||||||.:|..|.:|.:||...|
 Frog   263 EPMLNAAQEQFGGNPFASLVSNASNA-GNQPSRTENRDPLPNPWAPPSSTAGSTSTGSTTGANS- 325

Human   342 SGNSSSNATGNTVAAANYVASIFSTPGMQSLLQQITENPQLIQNMLSAPYMRSMMQSLSQNPDLA 406
            :|:|::..|.:|:  .|..|.:|:|||||||:|||||||||:||||||||||||||||||||:||
 Frog   326 TGSSTTTTTSSTL--PNLGAGMFNTPGMQSLMQQITENPQLMQNMLSAPYMRSMMQSLSQNPELA 388

Human   407 AQMMLNSPLFTANPQLQEQMRPQLPAFLQQMQNPDTLSAMSNPRAMQALMQIQQGLQTLATEAPG 471
            ||:|.|:|||:.|||||||||.|||.||||||||:||||||||||||||:||||||||||||||.
 Frog   389 AQVMQNNPLFSGNPQLQEQMRQQLPFFLQQMQNPETLSAMSNPRAMQALLQIQQGLQTLATEAPS 453

Human   472 LIPSFTPGVGVGVLGTAIGPVGPVTPIGPIGPIVPFTPIGPIGPIGPTGPAAPPGSTGSGGPTGP 536
            |:|...|                                 |.|.:|  .|.:.|.|
 Frog   454 LMPRTNP---------------------------------PFGGLG--SPNSSPAS--------- 474

Human   537 TVSSAAPSETTSP---TSESGPNQQFIQQMVQALAGANAP-QLPNPEVRFQQQLEQLNAMGFLNR 597
             |.|:||:|.:||   .||.| :|||||||:|||:|||.. |.||||||||.|||||:|||||||
 Frog   475 -VPSSAPTENSSPLSGLSEPG-HQQFIQQMLQALSGANPQNQNPNPEVRFQPQLEQLSAMGFLNR 537

Human   598 EANLQALIATGGDINAAIERLLGSQPS 624
            |||||||||||||||||||||||||||
 Frog   538 EANLQALIATGGDINAAIERLLGSQPS 564

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
UBQLN2	NP_038472.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..32		4/14 (29%)
		Ubl_PLICs	31..103	CDD:340506	63/71 (89%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	106..141		9/34 (26%)
		STI1	182..215	CDD:128966	30/32 (94%)
		STI1	208..253	CDD:450205	42/44 (95%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	287..349		37/61 (61%)
		STI1	382..426	CDD:128966	36/43 (84%)
		12 X 3 AA tandem repeats of P-X-X	491..526		4/34 (12%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	512..556		16/46 (35%)
		UBA_PLICs	581..620	CDD:270582	36/38 (95%)
ubqln1	NP_989221.1	Ubl_PLICs	17..89	CDD:340506	63/71 (89%)
		STI1	194..238	CDD:450205	41/43 (95%)
		STI1	364..396	CDD:128966	27/31 (87%)
		UBA_PLICs	521..560	CDD:270582	36/38 (95%)