DRSC/TRiP Functional Genomics Resources

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Protein Alignment UBQLN2 and ubqln4

DIOPT Version :8

Sequence 1:NP_038472.2 Gene:UBQLN2 / 29978 HGNCID:12509 Length:624 Species:Homo sapiens
Sequence 2:NP_998521.2 Gene:ubqln4 / 334337 ZFINID:ZDB-GENE-030131-6269 Length:599 Species:Danio rerio

Alignment Length:647 Identity:390/648 (60%)
Similarity:469/648 (72%) Gaps:71/648 (11%)


Human     1 MAENGESSGPPRPSRGPAA---AQGSAAAPAEPKIIKVTVKTPKEKEEFAVPENSSVQQFKEAIS 62
            ||||..:.        ||.   .:.:|||.|  .||||||||||:|||.|:.|::||.||||.||
Zfish     1 MAENSGTD--------PAVETNTEENAAASA--TIIKVTVKTPKDKEEIAIAEDASVAQFKEEIS 55

Human    63 KRFKSQTDQLVLIFAGKILKDQDTLIQHGIHDGLTVHLVIKSQNRPQGQSTQPSNA--------- 118
            ||||::.||||||||||||||.|||.||||.||||||||||:..:..|..:..::|         
Zfish    56 KRFKAKQDQLVLIFAGKILKDGDTLGQHGIKDGLTVHLVIKTAQKTSGAGSSQTSASSGPGPSQG 120

Human   119 --AGTNTTSAS----TPRSNSTPISTNSNPFG-LGSLGGLAGLSSLGLSSTNFSELQSQMQQQLM 176
              :||:|.|.:    ||: .|.|..|.|.|.. |...|.|:|||:||:.|.||.|||.|||:|||
Zfish   121 SPSGTDTPSPAGNLGTPQ-GSGPSPTPSQPANILAGFGDLSGLSNLGMGSANFMELQQQMQRQLM 184

Human   177 ASPEMMIQIMENPFVQSMLSNPDLMRQLIMANPQMQQLIQRNPEISHLLNNPDIMRQTLEIARNP 241
            ::|||:.||||||.||||:||||||||:||||||||||::|||||||:||||::||||:|:||||
Zfish   185 SNPEMLSQIMENPLVQSMMSNPDLMRQMIMANPQMQQLMERNPEISHMLNNPELMRQTMELARNP 249

Human   242 AMMQEMMRNQDLALSNLESIPGGYNALRRMYTDIQEPMLNAAQEQFGGNPFASVGSSSSSGEGTQ 306
            |||||||||||.||||||||||||||||||||||||||.:||:||||.|||:::|.:..: .|||
Zfish   250 AMMQEMMRNQDRALSNLESIPGGYNALRRMYTDIQEPMFSAAREQFGNNPFSALGGNGEN-PGTQ 313

Human   307 PSRTENRDPLPNPWAPP---PATQSSATTSTTTSTGSGSGNSSSNATGNTVAAANYVASIFSTPG 368
            |||||||:||||||.||   .:|.||.|.:||:||.|.:..|.||..|  ::::|....:|::||
Zfish   314 PSRTENREPLPNPWGPPDGTASTTSSGTPTTTSSTTSSTTPSVSNPLG--ISSSNLGNGMFNSPG 376

Human   369 MQSLLQQITENPQLIQNMLSAPYMRSMMQSLSQNPDLAAQMMLNSPLFTANPQLQEQMRPQLPAF 433
            ||||:|||:|||||:|||:||||||:|||||:||||:|:|:::|:|||..|||||||||.|||.|
Zfish   377 MQSLMQQISENPQLMQNMISAPYMRTMMQSLAQNPDVASQVLMNNPLFAGNPQLQEQMRQQLPVF 441

Human   434 LQQMQNPDTLSAMSNPRAMQALMQIQQGLQTLATEAPGLIPSFTPGVGVGVLGTAIGPVGPVTPI 498
            |||||||:.||.|:|||||:||||||:|||||.||||||:|...||...|  |..:|..|...|.
Zfish   442 LQQMQNPEALSVMTNPRAMRALMQIQEGLQTLQTEAPGLMPGLGPGGMPG--GIPVGMPGAPLPT 504

Human   499 GPIGPIVPFTPIGPIGPIGPTGPAAPPGSTGSGGPTGPTVSSAAPSETTSPTSESGP-NQQFIQQ 562
            |     |..||..|           ||...||               |.:||:.:.| .||.:||
Zfish   505 G-----VTVTPENP-----------PPSGQGS---------------TPTPTAGASPAQQQLMQQ 538

Human   563 MVQALAGANAPQLPNPEVRFQQQLEQLNAMGFLNREANLQALIATGGDINAAIERLLGSQPS 624
            |:|..||.:| ....||||||||||||:||||:|||||||||||||||||||||||||||||
Zfish   539 MLQMFAGGSA-STQTPEVRFQQQLEQLSAMGFINREANLQALIATGGDINAAIERLLGSQPS 599

Known Domains:


GeneSequenceDomainRegion External IDIdentity
UBQLN2NP_038472.2 UBQ 33..103 CDD:214563 56/70 (80%)
hPLIC_N 33..103 CDD:176403 56/70 (80%)
STI1 382..426 CDD:128966 32/44 (73%)
12 X 3 AA tandem repeats of P-X-X 491..526 9/35 (26%)
UBA_PLICs 581..620 CDD:270582 37/39 (95%)
ubqln4NP_998521.2 UBQ 26..96 CDD:214563 56/70 (80%)
hPLIC_N 26..96 CDD:176403 56/70 (80%)
STI1 186..223 CDD:128966 31/37 (84%)
UBA_PLICs 556..595 CDD:270582 37/39 (95%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
eggNOG 1 0.900 E1_COG5272
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 D1553668at2759
OrthoFinder 1 1.000 FOG0000468
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 1 0.900 OOG5_127163
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
43.810

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