Protein Alignment UBQLN2 and Ubqln2

DIOPT Version :8

• Sequence 1: NP_038472.2
• Gene: UBQLN2 / 29978
• HGNCID: 12509
• Length: 624
• Species: Homo sapiens
• Sequence 2: NP_001101721.1
• Gene: Ubqln2 / 317396
• RGDID: 1563566
• Length: 638
• Species: Rattus norvegicus
• Alignment Length: 641
• Identity: 553/642 (86%)
• Similarity: 590/642 (92%)
• Gaps: 20/642 (3%)

Human     1 MAENGESSGPPRPSRGPAAAQGSAAAPAEPKIIKVTVKTPKEKEEFAVPENSSVQQFKEAISKRF 65
            ||||||||||||||||||||.|:|..||||||||||||||||||||||||||:||||||||||||
  Rat     1 MAENGESSGPPRPSRGPAAAPGAANPPAEPKIIKVTVKTPKEKEEFAVPENSTVQQFKEAISKRF 65

Human    66 KSQTDQLVLIFAGKILKDQDTLIQHGIHDGLTVHLVIKSQNRPQGQ-STQPSNAAGTNTTSAST- 128
            |||||||||||||||||||||||||||||||||||||||||||||| :||||..|||:||:.:|
  Rat    66 KSQTDQLVLIFAGKILKDQDTLIQHGIHDGLTVHLVIKSQNRPQGQATTQPSTTAGTSTTTTTTT 130

Human   129 -------------PRSNSTPISTNSNPFGLGSLGGLAGLSSLGLSSTNFSELQSQMQQQLMASPE 180
                         ||.::|..:|||:..||||   ||.|.:|||:|:||:|||:||||||:||||
  Rat   131 TAAAPPAATTSSAPRCSTTATTTNSSNLGLGS---LASLGNLGLNSSNFTELQNQMQQQLLASPE 192

Human   181 MMIQIMENPFVQSMLSNPDLMRQLIMANPQMQQLIQRNPEISHLLNNPDIMRQTLEIARNPAMMQ 245
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Rat   193 MMIQIMENPFVQSMLSNPDLMRQLIMANPQMQQLIQRNPEISHLLNNPDIMRQTLEIARNPAMMQ 257

Human   246 EMMRNQDLALSNLESIPGGYNALRRMYTDIQEPMLNAAQEQFGGNPFASVGSSSSSGEGTQPSRT 310
            ||||||||||||||||||||||||||||||||||||||||||||||||:||||||||||||||||
  Rat   258 EMMRNQDLALSNLESIPGGYNALRRMYTDIQEPMLNAAQEQFGGNPFATVGSSSSSGEGTQPSRT 322

Human   311 ENRDPLPNPWAPPPATQSSA-TTSTTTSTGSGSG-NSSSNATGNTVAAANYVASIFSTPGMQSLL 373
            ||||||||||||||.||:|| ||:||||:|:.:| |:||...|||:|||||||||||||||||||
  Rat   323 ENRDPLPNPWAPPPTTQTSATTTTTTTSSGTVAGSNTSSTTAGNTMAAANYVASIFSTPGMQSLL 387

Human   374 QQITENPQLIQNMLSAPYMRSMMQSLSQNPDLAAQMMLNSPLFTANPQLQEQMRPQLPAFLQQMQ 438
            |||||||||||||||||||||||||||||||:||||||:|||||||||||||||||||.||||||
  Rat   388 QQITENPQLIQNMLSAPYMRSMMQSLSQNPDMAAQMMLSSPLFTANPQLQEQMRPQLPNFLQQMQ 452

Human   439 NPDTLSAMSNPRAMQALMQIQQGLQTLATEAPGLIPSFTPGVGVGVLGTAIGPVGPVTPIGPIGP 503
            :|:|::|||||||||||:||||||||||||||||||.||||||||||||||.|||||||||||||
  Rat   453 SPETIAAMSNPRAMQALLQIQQGLQTLATEAPGLIPGFTPGVGVGVLGTAITPVGPVTPIGPIGP 517

Human   504 IVPFTPIGPIGPIGPTGPAAPPGSTGSGGPTGPTVSSAAPSETTSPTSESGPNQQFIQQMVQALA 568
            |||||||||||||||||||:.|||||:|.|...||||:||:||.||||||||:|||||||||||.
  Rat   518 IVPFTPIGPIGPIGPTGPASSPGSTGTGIPPATTVSSSAPTETISPTSESGPSQQFIQQMVQALT 582

Human   569 GANAPQLPNPEVRFQQQLEQLNAMGFLNREANLQALIATGGDINAAIERLLGSQPS 624
            |.:.||.|||||||||||||||||||||||||||||||||||||||||||||||||
  Rat   583 GGSPPQPPNPEVRFQQQLEQLNAMGFLNREANLQALIATGGDINAAIERLLGSQPS 638

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
UBQLN2	NP_038472.2	UBQ	33..103	CDD:214563	69/70 (99%)
		hPLIC_N	33..103	CDD:176403	69/70 (99%)
		STI1	382..426	CDD:128966	42/44 (95%)
		12 X 3 AA tandem repeats of P-X-X	491..526		33/35 (94%)
		UBA_PLICs	581..620	CDD:270582	39/39 (100%)
Ubqln2	NP_001101721.1	UBQ	33..103	CDD:214563	69/70 (99%)
		hPLIC_N	33..103	CDD:176403	69/70 (99%)
		STI1	194..227	CDD:128966	33/33 (100%)
		STI1	393..440	CDD:128966	45/47 (96%)
		UBA_PLICs	595..634	CDD:270582	39/39 (100%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930				C156737766
eggNOG	1	0.900				E1_COG5272
HGNC	1	1.500
Hieranoid	1	1.000
Homologene	1	1.000				H81830
Inparanoid	1	1.050	1070	1.000	Inparanoid score	I4712
OMA	1	1.010
OrthoDB	1	1.010				D116115at9347
OrthoFinder	1	1.000				FOG0000468
OrthoInspector	1	1.000				T2465829
orthoMCL	1	0.900				OOG5_127163
Panther	1	1.100			LDO	PTHR10677
Phylome	1	0.910		0.800	Consistency score
TreeFam	1	0.960
	14	14.270