Protein Alignment UBQLN2 and dph1

DIOPT Version :8

• Sequence 1: NP_038472.2
• Gene: UBQLN2 / 29978
• HGNCID: 12509
• Length: 624
• Species: Homo sapiens
• Sequence 2: NP_594159.1
• Gene: dph1 / 2542667
• PomBaseID: SPAC26A3.16
• Length: 354
• Species: Schizosaccharomyces pombe
• Alignment Length: 598
• Identity: 124/599 (21%)
• Similarity: 191/599 (32%)
• Gaps: 261/599 (44%)

Human    33 IKVTVKTPK-EKEEFAVPENSSVQQFKEAISKRFKSQTDQLVLIFAGKILKDQDTLIQHGIHDGL 96
            |.:|:|... :|....|...|||...||||:.....:.::..||:||::|||:::|..:.|.||.
pombe     4 ISLTIKAANDQKYAVTVDSESSVLALKEAIAPVADIEKERQRLIYAGRVLKDEESLKTYKIQDGH 68

Human    97 TVHLVIKSQNRPQGQSTQPSNAAGTNTTSASTPRSNSTPISTNSNPFGLGSLGGLAGLSSLGLSS 161
            ::|||               ...|.|..:|:|..|:.|
pombe    69 SIHLV---------------KTLGQNPAAAATNVSDRT--------------------------- 91

Human   162 TNFSELQSQMQQQLMASPEMMIQIMENPFVQSMLSNPDLMRQLIMANPQMQQLIQRNPEISHLLN 226
                                                               |.:..|.:.....|
pombe    92 ---------------------------------------------------QQVPTNIQAGQGAN 105

Human   227 NPDIMRQTLEIARNPAMMQEMMRNQDLALSNLESIPGGYNALRRMYTDIQEPMLNAAQEQFGGNP 291
            ||                          |:||.|         ..|.....||.:|:  .||.||
pombe   106 NP--------------------------LANLTS---------ARYAGFNIPMPSAS--MFGPNP 133

Human   292 FASVGSSSSSGEGTQPSRTENRDPLPNPWAPPPATQSSATTSTTTSTGSGSGNSSSNATGNTVAA 356
                                     .||  .||:|:.
pombe   134 -------------------------ENP--VPPSTEE---------------------------- 143

Human   357 ANYVASIFSTPGMQSLLQQITENPQLIQNML-SAPYMRSMMQSLSQNPDLAAQMMLNSPLFTANP 420
               :|::.|.|.:||.:.::..|||::..:: |:|::|                  |:|
pombe   144 ---LANMLSNPMVQSSINEMFSNPQMLDMIINSSPHLR------------------NAP------ 181

Human   421 QLQEQMRPQLPAFLQQMQNPDTLSAMSNPRAMQALMQIQQGLQTLATEAPGLIPSFTPGVGVGVL 485
                      |...|.||:|:...||::|..|:.:.|:.|.:.....:...|:.....|.|:|.|
pombe   182 ----------PYVRQMMQSPEFRRAMTDPDTMRQMAQLHQQMGAAGIDPMSLMGGGLGGAGLGGL 236

Human   486 GTA-IGPVG-------PVTPIGPIGPIVPFTPI-GPIGPIGPTGPAAPPGSTGSGGPTGPTVSSA 541
            |.| :|..|       .:....|:........| ..:..:|..|..|..|..|.|...|...|..
pombe   237 GGAGLGGFGGANNATAGIAGAAPVDQTAAANTIQNLLNNLGGAGFGAGLGDAGLGAGLGGAASPP 301

Human   542 APSETTSPTSESGPNQQFIQQMVQALAGANAPQLPNPEVRFQQQLEQLNAMGFLNREANLQALIA 606
            ||::.|.|                            ||.|:.:||.|||.|||::.|.|:|||..
pombe   302 APAQDTRP----------------------------PEERYAEQLSQLNEMGFVDFERNVQALRR 338

Human   607 TGGDINAAIERLL 619
            :||::..|||.||
pombe   339 SGGNVQGAIESLL 351

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
UBQLN2	NP_038472.2	UBQ	33..103	CDD:214563	26/71 (37%)
		hPLIC_N	33..103	CDD:176403	26/71 (37%)
		STI1	382..426	CDD:128966	5/45 (11%)
		12 X 3 AA tandem repeats of P-X-X	491..526		6/43 (14%)
		UBA_PLICs	581..620	CDD:270582	21/40 (53%)
dph1	NP_594159.1	UBQ	4..75	CDD:214563	26/86 (30%)
		Scythe_N	4..75	CDD:176404	26/86 (30%)
		STI1	142..180	CDD:128966	12/87 (14%)
		UBA_Dsk2p_like	310..351	CDD:270509	22/41 (54%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000				FOG0000468
OrthoInspector	1	1.000				T998898
orthoMCL	1	0.900				OOG5_127163
Panther	1	1.100			O	PTHR10677
Phylome	1	0.910		0.947	Consistency score
RoundUp	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.910