Protein Alignment: CYP2S1 and Cyp303a1

• Sequence 1: NP_085125.1
• Gene: CYP2S1
• HGNCID: 15654
• Length: 504
• Species: Homo sapiens
• Sequence 2: NP_001285977.1
• Gene: Cyp303a1
• FlyBaseID: FBgn0001992
• Length: 503
• Species: Drosophila melanogaster
• Alignment Length: 492
• Identity: 133/493 (27%)
• Similarity: 228/493 (46%)
• Gaps: 44/493 (9%)

Human    18 LLTLALSGTRARGHLPPGPTPLPLLGNLLQL-----RPGALYSGLMRLSKKYGPVFTIY---LGP 74
            ||.:...|.|.....||||...|::|:.||:     |.|.....:...:::|...:..|   :|.
  Fly    13 LLAILFGGVRKPKRFPPGPAWYPIVGSALQVSQLRCRLGMFCKVIDVFARQYVNPYGFYGLKIGK 77

Human    75 WRPVVVLVGQEAVREALGGQAEEFSGR--GTVAMLEGTFDGH-GVFFSNGERWRQLRKFTMLALR 136
            .: ||:....:|:.|.:..  |:..||  |....|. ||:.. ||..::||.|.:.|:|.:..|:
  Fly    78 DK-VVIAYTNDAISEMMTN--EDIDGRPDGIFYRLR-TFNSRLGVLLTDGEMWVEQRRFILRHLK 138

Human   137 DLGMGKREGEELIQAEARCLVETFQ------GTEGRPFDPSLLLAQATSNVVCSLLFGLRFSYED 195
            :.|..:....:::..||.||::..:      |.:....:...|.:....|.:..:|.|.|:....
  Fly   139 NFGFARSGMMDIVHNEATCLLQDLKDKVLKSGGKQTRIEMHDLTSVYVLNTLWCMLSGRRYEPGS 203

Human   196 KEFQAVVRAAGGTLLGVSSQGGQTYEMFSW-----FLRPLPGPHKQLLHHVSTLAAFTVRQVQQH 255
            .|...::.........:...|.    :||.     |:.|....:...:....:|..|..::::.|
  Fly   204 PEITQLLETFFELFKNIDMVGA----LFSHFPLLRFIAPNFSGYNGFVESHRSLYTFMSKEIELH 264

Human   256 QGNLDASGPARDLVDAFLLKMAQEEQNPGT-EFTNKNMLMTVIYLLFAGTMTVSTTVGYTLLLLM 319
            :.........|||:|::|  .||:|.|... .|:::::|...:.:..||:.|.:.::|:..:.|:
  Fly   265 RLTYKNYDEPRDLMDSYL--RAQDEGNDEKGMFSDQSLLAICLDMFLAGSETTNKSLGFCFMHLV 327

Human   320 KYPHVQKWVREELNRELGAGQAPSLG-DRTRLPYTDAVLHEAQRLLALVPMGIPRTLMRTTRFRG 383
            ..|.:|:...:|:...:|..:.|... |||:|||.:|:..||.|:..|...|||...:..||..|
  Fly   328 LQPEIQERAFQEIKEVVGLERIPEWSRDRTKLPYCEAITLEAVRMFMLHTFGIPHRAVCDTRLSG 392

Human   384 YTLPQGTEVFPLLGSILHDPNIFKHPEEFNPDRFLDADGRFRKHEAFLPFSLGKRVCLGEGLAKA 448
            |.:|:.|.|......:|.:|..|..||.|||||:| .||..:..|||.||..|:..|:|:.|.:.
  Fly   393 YEIPKDTMVIACFRGMLINPVDFPDPESFNPDRYL-FDGHLKLPEAFNPFGFGRHRCMGDLLGRQ 456

Human   449 ELFLFFTTILQAFSL---------ESPCPPDTLSLKP 476
            .||:|.||:||.|.:         |.|....|.::||
  Fly   457 NLFMFTTTVLQNFKMVAIPGQVPEEVPLEGATAAVKP 493

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CYP2S1	NP_085125.1	p450	49..492	CDD:306555	121/457 (26%)
Cyp303a1	NP_001285977.1	p450	28..480	CDD:278495	124/463 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930				C112520444
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910		0.667	Consistency score
RoundUp	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.840