Protein Alignment GSTT2 and GstT1

DIOPT Version :10

• Sequence 1: NP_000845.2
• Gene: GSTT2 / 2953
• HGNCID: 4642
• Length: 244
• Species: Homo sapiens
• Sequence 2: NP_610509.2
• Gene: GstT1 / 35995
• FlyBaseID: FBgn0050000
• Length: 228
• Species: Drosophila melanogaster
• Alignment Length: 233
• Identity: 75/233 - (32%)
• Similarity: 111/233 - (47%)
• Gaps: 25/233 - (10%)

Human     3 LELFLDLVSQPSRAVYIFAKKNGIPLELRTVDLVKGQHKSKEFLQINSLGKLPTLKDGDFILTES 67
            ::.:.|.:||||||::|..|....|.|...|.|.|.:..:.|:..||...|:|.:.||.|.|.||
  Fly     5 IKYYYDFLSQPSRALWIAMKLGKTPFEDCPVALRKQEQLTDEYRSINRFQKVPAIVDGKFQLGES 69

Human    68 SAILIYLSCKYQTPDHWYPSDLQARARVHEYLGWHADCIR---GTFGIPLWVQVLGPLIGV-QVP 128
            .:|:.||:.|....:..||..|:.||||.|:|.|....:|   ..|...:|   |.|..|: ..|
  Fly    70 VSIVRYLADKGVFSEQLYPKTLEERARVDEFLEWQHFNVRLVCSLFFRQVW---LLPAKGLAPAP 131

Human   129 K--------EKVERNRTAMDQALQWLEDKFLGDRPFLAGQQVTLADLMALEELMQPVALGYELFE 185
            |        :.||.|...:::.  |||      :.||.|.::|:||:....|:.|.....|.:.|
  Fly   132 KPESVKKLIKDVESNLGLLERL--WLE------KDFLVGDKLTVADIFGSSEINQMKLCQYNVNE 188

Human   186 GR-PRLAAWRGRVEAFLGAELCQEAHSIILSILEQAAK 222
            .: |::|.|..||..... ....||||.:....:||.|
  Fly   189 KQFPKVAKWMERVRDATN-PYYDEAHSFVYKTSQQAVK 225

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GSTT2	NP_000845.2	GST_N_Theta	3..78	CDD:239348	28/74 (38%)
		GST_C_Theta	91..216	CDD:198292	40/137 (29%)
GstT1	NP_610509.2	GST_N_Theta	5..80	CDD:239348	28/74 (38%)
		GST_C_Theta	93..218	CDD:198292	40/136 (29%)