Protein Alignment Cyp2c7 and Cyp303a1

DIOPT Version :10

• Sequence 1: NP_058854.1
• Gene: Cyp2c7 / 29298
• RGDID: 620379
• Length: 490
• Species: Rattus norvegicus
• Sequence 2: NP_652070.1
• Gene: Cyp303a1 / 49165
• FlyBaseID: FBgn0001992
• Length: 503
• Species: Drosophila melanogaster
• Alignment Length: 518
• Identity: 134/518 - (25%)
• Similarity: 241/518 - (46%)
• Gaps: 56/518 - (10%)

  Rat     6 FLVLTLSSLILLSLWRQSSRR-RKLPPGPTPLPIIGNFLQID---------VKNISQSLTKFSKT 60
            :.|:.:....||::.....|: ::.||||...||:|:.||:.         .|.|.....::...
  Fly     3 YTVIWIFCATLLAILFGGVRKPKRFPPGPAWYPIVGSALQVSQLRCRLGMFCKVIDVFARQYVNP 67

  Rat    61 YGPVFTLYLGSQPTVILHGYEAIKEALIDNGEKFSGR--GSYPMNENVTKGFGIVFSNGNRWKEM 123
            || .:.|.:|....||.:..:||.|.:  ..|...||  |.:..........|::.::|..|.|.
  Fly    68 YG-FYGLKIGKDKVVIAYTNDAISEMM--TNEDIDGRPDGIFYRLRTFNSRLGVLLTDGEMWVEQ 129

  Rat   124 RRFTIMNFRNLGIGKRNIEDRVQEEAQCLVEELR----KTKGSPCDPSL-------ILNCAPCNV 177
            |||.:.:.:|.|..:..:.|.|..||.||:::|:    |:.|......:       :||...|
  Fly   130 RRFILRHLKNFGFARSGMMDIVHNEATCLLQDLKDKVLKSGGKQTRIEMHDLTSVYVLNTLWC-- 192

  Rat   178 ICSITFQNHFDYKDKEMLTFMEKVNENLKIMSSPWMQVCNSFPSLIDYFP---------GTHHKI 233
               :.....::....|:...:|...|..|.:        :...:|..:||         ..::..
  Fly   193 ---MLSGRRYEPGSPEITQLLETFFELFKNI--------DMVGALFSHFPLLRFIAPNFSGYNGF 246

  Rat   234 AKNINYMKSYLLKKIEEHQESL-DVTNPRDFVDYYLIKQKQANNIEQSEYSHENLTCSIMDLIGA 297
            .::...:.:::.|:||.|:.:. :...|||.:|.||..|.:.|: |:..:|.::|....:|:..|
  Fly   247 VESHRSLYTFMSKEIELHRLTYKNYDEPRDLMDSYLRAQDEGND-EKGMFSDQSLLAICLDMFLA 310

  Rat   298 GTETMSTTLRYALLLLMKYPHVTAKVQEEIDRVIGRHRSP-CMQDRKHMPYTDAMIHEVQRFINF 361
            |:||.:.:|.:..:.|:..|.:..:..:||..|:|..|.| ..:||..:||.:|:..|..|....
  Fly   311 GSETTNKSLGFCFMHLVLQPEIQERAFQEIKEVVGLERIPEWSRDRTKLPYCEAITLEAVRMFML 375

  Rat   362 VPTNLPHAVTCDIKFRNYLIPKGTKVLTSLTSVLHDSKEFPNPEMFDPGHFLDENGNFKKSDYFL 426
            ....:||...||.:...|.|||.|.|:.....:|.:..:||:||.|:|..:|.: |:.|..:.|.
  Fly   376 HTFGIPHRAVCDTRLSGYEIPKDTMVIACFRGMLINPVDFPDPESFNPDRYLFD-GHLKLPEAFN 439

  Rat   427 PFSAGKRACVGEGLARMQLFLFLTTILQNFNLKSLVHPKDI-DTMPVLNGFASLPPTYQLCFI 488
            ||..|:..|:|:.|.|..||:|.||:||||.:.::  |..: :.:|:....|::.| |.:..:
  Fly   440 PFGFGRHRCMGDLLGRQNLFMFTTTVLQNFKMVAI--PGQVPEEVPLEGATAAVKP-YDIMLV 499

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp2c7	NP_058854.1	CYP2C-like	61..485	CDD:410758	119/448 (27%)
Cyp303a1	NP_652070.1	CYP15A1-like	68..496	CDD:410744	119/448 (27%)