Protein Alignment Dhrs7b and CG31937

DIOPT Version :10

• Sequence 1: NP_001008507.1
• Gene: Dhrs7b / 287380
• RGDID: 1311243
• Length: 325
• Species: Rattus norvegicus
• Sequence 2: NP_608616.2
• Gene: CG31937 / 326177
• FlyBaseID: FBgn0031360
• Length: 321
• Species: Drosophila melanogaster
• Alignment Length: 286
• Identity: 89/286 - (31%)
• Similarity: 146/286 - (51%)
• Gaps: 13/286 - (4%)

  Rat    46 SKAYLRNAVVVVTGATSGLGKECARVFHAAGAKVVLCGRNVKALEEFTRELADSSSSQGQTHQPC 110
            |.:.:|..||.:|||:||:|:..|......|.|:||..|.::.||:...|...::.....|....
  Fly    40 SLSSMRGQVVWITGASSGIGRALALSLARHGVKLVLSARRLEQLEQVQEECLAAARGLLATKDVL 104

  Rat   111 VVTFDLADPGAIAPAAAEILQCFGYVDILINNAGISYRGAISDTIVDVDRKVMEINYFGPVALTK 175
            |:..|:.|..........:|..|..:|:|:||||.|.|.:.::..::|||::.|::.|..|.|::
  Fly   105 VIQMDMLDLDEHKTHLNTVLNHFHRLDVLVNNAGRSQRASWTEVEIEVDRELFELDVFAVVHLSR 169

  Rat   176 ALLPSMVERK--RGHIVAISSIQGKISIPFRSAYAASKHATQAFFDCLRAEMKDSDIEVTVISPG 238
            .::...||:.  ||||.|.|||.|...:||...|.|:|||..|:...|:.||:  .::|::.:||
  Fly   170 LVVRYFVEQNGGRGHIAATSSIAGFSPVPFSPTYCAAKHALNAYLLSLKVEMR--KLDVSLFAPG 232

  Rat   239 YIHTNLSVNAVTADGSRYGALDKNTA-QGRSAVEVAQDIFDAVGKKKKDVLLTDFLPT--MAVYI 300
            .|.|:....|.|  ||:.|.:..:|| |.|...:...|:|......|.|:......|.  :|...
  Fly   233 PIATDFLQEAFT--GSQGGKVGLSTANQKRMTAQRCGDLFAVALANKMDLTWCGLFPVNLLAYCA 295

  Rat   301 R--TLAPRLFFRIMASRA-RKERKSK 323
            |  ||: ::..::|..:. .|.|:.|
  Fly   296 RNPTLS-KILAQLMTEKTLNKIREGK 320

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dhrs7b	NP_001008507.1	11beta-HSD1_like_SDR_c	50..311	CDD:187593	84/267 (31%)
CG31937	NP_608616.2	Rossmann-fold NAD(P)(+)-binding proteins	44..293	CDD:473865	80/252 (32%)