Protein Alignment: CCDC66 and CG13251

• Sequence 1: NP_001340076.1
• Gene: CCDC66
• HGNCID: 27709
• Length: 954
• Species: Homo sapiens
• Sequence 2: NP_649246.1
• Gene: CG13251
• FlyBaseID: FBgn0037014
• Length: 1088
• Species: Drosophila melanogaster
• Alignment Length: 642
• Identity: 131/643 (20%)
• Similarity: 234/643 (36%)
• Gaps: 194/643 (30%)

Human   423 HIAKPIKDVVMANSKKTNFLRSMTALLDPAQIEERDRRRQKQLEHQKAITAQVEEKRRKKQLEEE 487
            |..|..:|.|.:....:.:||...|.||...:.||..:|:|..|:..||..|:.|:...::.|.|
  Fly   445 HDLKDSEDDVQSMQSSSTYLRGQNAPLDAHTLAERMDKRRKAAEYHNAIKKQLHERELIRKWEHE 509

Human   488 QRKKEEQEEELRLAQEREEMQKQYEEDILKQKQKEEIMTLKTNELFQTMQRAQELAQRLKQEQR- 551
            :.::|||.||.|:.::::..|::.|.:....:::||....|...:...:|:|:..|:..:|::|
  Fly   510 RHRQEEQIEEERIRRQKQLEQERLEFERRTLQEREEAQQKKQQVMLDAIQKAEVAAKMERQKRRM 574

Human   552 IRELAQKGHDT----SRLIKNLGGDFSLPVDTIQMEYNASNISNSRHDSDEISGKMN-TYMNSTT 611
            :|:.::...:|    |.||:         |.:::.|          .|::|.||.:. ......|
  Fly   575 VRQPSKVSQETEEDESELIR---------VQSVEEE----------EDAEEKSGAVEPPSQEEET 620

Human   612 SKKDTG----VQTDDLNIGIFTNAESHCGSLMERDITN-CSSPEISAELIGQFSTKKNKQELTQD 671
            |....|    :..:.:.||...|        :.|.||. ...|        :.|.|::.:|.||.
  Fly   621 SNTPRGAPPVMSEEKVLIGTPIN--------LRRTITKPIKQP--------RDSRKEDPKEPTQT 669

Human   672 KGASL----EKENNRCNDQ----------------CNQFTRIEKQTKHMKKYPKRPDWNINKPPK 716
            |..:.    :|||.....|                .|....::..|..|:.       .:.|||:
  Fly   670 KVQTTFLGEDKENVALLMQPATLIPLPVTSDIFGLQNAIGNLQIATYFMQP-------PMQKPPE 727

Human   717 RYIPASEKYPK-----------------QLQKQREEKKVRR------------------------ 740
              .|.|  |.|                 |.:|:.:.....|
  Fly   728 --TPGS--YSKATMTHRTDTSIYTEDGYQAEKEEDPLTTARSGRTDLVTASGCFSPDSLEVDVAP 788

Human   741 ----QMELLHLVEKNNPGHL-----SQNRG-ISPEIFHSSHQETESKLRWHLVKKEEEPLN---- 791
                :.:.|.|:....|..|     |.:|| .:.|:.|.:..||:::|          |||
  Fly   789 VLIAETDKLALIPLKTPLQLGISNSSDDRGEHNHEVGHQADVETQTEL----------PLNCDLC 843

Human   792 -IHS------FSKERSPSSPVPVVKNRTQQTQNTLHLPLKNSSYERENLISGSNQTELSSGI--- 846
             .|.      ..:|.|.::.....|::||        |.|.|:.|:::..:.:..|..::..
  Fly   844 LFHDNFYKVLLKREVSTTTTTQTSKSQTQ--------PAKESTAEKDHETTTTTTTTTTTTFKAK 900

Human   847 SESSHFIPYVRTN-----EIYYLDPDAPLSGPSTQDPQYQNSQDCGQKRQLFDSDCVRDPLLNPN 906
            |:.......::.|     :...:| |.|..|.:....||..:.|       .|..|:|....:|:
  Fly   901 SKDKDKEKNLKRNLNKDKDANKMD-DRPKWGVNRPVVQYVKASD-------RDPFCLRKKKNHPS 957

Human   907 MVK----------------NRDRQQAILKG----LSEL-RQGLLQKQKELESSLLPL 942
            ..|                ..||...|..|    ..|| .:|.|.|.:.:.:.:||:
  Fly   958 TAKPPRSLSMDSRLDSVALPEDRLINIAGGPPSAAGELEEEGFLLKARNVCTEILPI 1014

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCDC66	NP_001340076.1	CCDC66	411..562	CDD:317619	37/140 (26%)
CG13251	NP_649246.1	CCDC66	445..580	CDD:291889	37/135 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930				C333947892
eggNOG	1	0.900				E1_28UYI
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100			LDO	PTHR22736
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.930