Protein Alignment CG33298 and atp10b

DIOPT Version :10

• Sequence 1: NP_995666.1
• Gene: CG33298 / 2768929
• FlyBaseID: FBgn0032120
• Length: 1517
• Species: Drosophila melanogaster
• Sequence 2: XP_017214606.1
• Gene: atp10b / 563932
• ZFINID: ZDB-GENE-130530-796
• Length: 1294
• Species: Danio rerio
• Alignment Length: 1356
• Identity: 534/1356 - (39%)
• Similarity: 767/1356 - (56%)
• Gaps: 203/1356 - (14%)

  Fly   207 WWKRLTLCNYN-TGDKFEERSYRTVVPNHTVP-PKTPKRDHPNGQFVGNKIRTTKYTLLSFIPKN 269
            |...|||.... |..:.::|..|.||.|  :| ....||:.||.|:.||.|:|.||.|.||:|.|
Zfish     3 WTSPLTLFQRGWTRHRDQDRPIRKVVSN--LPFEDLRKREQPNRQYEGNAIKTNKYRLWSFLPMN 65

  Fly   270 LLEQFHRVANLYFIFIVLLNWVPEISAFGKEVAMIPVLFVLGVTAVKDLFEDRRRRASDKRINNT 334
            |.|||||:||:||:.:.:||::|.::||..|||:||:..:|.:|||||.:||.||..:|:::||.
Zfish    66 LFEQFHRLANIYFVGLAILNFIPVVNAFQPEVALIPICIILALTAVKDGWEDFRRYQTDQQLNNM 130

  Fly   335 TCRVYDGETERYKKVKWQELRVGDIVHLSNNETVPADILLLRTSDPQGVCYIDTCDLDGETNLKR 399
            .|.::......:.:.:|:::||||.|.:.:||.:|||||||.||||.|||:::|.:||||||||:
Zfish   131 PCFIFRRRLMCFVERRWKDVRVGDFVKVLSNEIIPADILLLHTSDPNGVCHMETANLDGETNLKQ 195

  Fly   400 REVVRGFEEMQSIFVPSKFVSRVEADAPTTKLYRFHGALIHPTGERVPISTECLLLRESRLKNTD 464
            |:||.||..:...|.|..|.|.|..:.|...|..|.|.:..|...|.....:.||||...::|||
Zfish   196 RKVVPGFSTLGEPFQPQTFDSTVVCENPNNNLNLFKGFIERPDKRRSGFGIDSLLLRGCTVRNTD 260

  Fly   465 YIEGIVVYAGHETKSMLNNSGPRYKRSQVEQQMNIDVIWCVIILLILCVVGAIGCRMWLSSFTHF 529
            ...||||||||||||||||:|||||||::|::||.||::||::|..:|::||:|..:||.:|:..
Zfish   261 DAAGIVVYAGHETKSMLNNNGPRYKRSKIERKMNTDVLFCVLLLFFMCLIGALGHAIWLETFSTM 325

  Fly   530 PVPYLPP----NKLTANMESMWIFWTYIVILQVMIPLSLYVTIELCKILQVFHIHNNVDLFDAET 590
            | .|:.|    |.:::.:...::|:|.|::||||||:||||:|||.|:.|:|.|..:.:|:|.|.
Zfish   326 P-SYIVPDSNGNYISSALAGFYMFFTMIILLQVMIPVSLYVSIELVKMGQIFFITQDAELYDQEL 389

  Fly   591 NKQTECRAMNITEELGQIQHIFTDKTGTLTENKMIFRRCVVNGSDYNHPPS-------------- 641
            :.:.:|||:||||:|||||::|:|||||||||||:|:||.:.|::|.|..:
Zfish   390 DSRVQCRALNITEDLGQIQYVFSDKTGTLTENKMVFKRCTIMGTEYCHEENAARLAVINGGGNEE 454

  Fly   642 ELEKIYSKPGAPAPPLIPNDNLNSD---------------------------------------- 666
            |...||.|  ...|||.|.:.|..|
Zfish   455 EEVTIYQK--TKLPPLFPLEELQDDHTGHKNHANTQVAAASRRRSKVAAGAQSDMAFSSPLETVV 517

  Fly   667 -------------MAQLTQGTYLTPHAQRIQEFLVVLAICNTVIVGAAPHRDMMNASGIIEVQQI 718
                         ||.:..|.||        :|.:.|||||||:|.... .......|.......
Zfish   518 VPDRKLMLEVDHQMASIQTGPYL--------DFFLALAICNTVVVSTLT-AQRQRVKGRRNSSYS 573

  Fly   719 GNSPANLKHG---KQRQKLLASSTSTTTTTTIINGPTTQPQVVSIPADRYIRLAESRSVTPSPPP 780
            |:|..|:...   ...||..:|                            :|...:|.....|
Zfish   574 GSSSHNMGQWFKISSLQKFFSS----------------------------MRFKRNRETMADP-- 608

  Fly   781 NLLFALPAQSHQPTLSPISSSAESSPNSESESPSPPMKNKSLSNSISPTGRAKAVINSKITSIAT 845
               ||:  ...:|....|||.::|.|..:                         ||:|
Zfish   609 ---FAI--DEDEPDTFHISSVSDSRPGQK-------------------------VISS------- 636

  Fly   846 FLNAKTQGKRMKLPSSKTGTIYRTADGRPL-------YEAESPDELALVNAAYSYDCCLLNRSPN 903
                  :||                |.|.|       |||.||||.||::||.:|...::.|:|.
Zfish   637 ------EGK----------------DKRSLSRSEEVCYEAHSPDEAALIHAAKAYGFTMVERTPR 679

  Fly   904 QILVSMPMAGATREYEILKVLPFDSSRKCMSIVVRQIGSQEIVLYTKGADSSIMPVLVPC-SHNS 967
            .:.|.:|.. ...::|:|.||.|||:|:.|||:||...:.||::|||||||::|..|... |..|
Zfish   680 YVTVKLPNE-TLLKFEVLDVLTFDSTRRRMSIIVRHPHTNEIIMYTKGADSAVMEKLGNVFSVES 743

  Fly   968 PEGILREQTQQLLDRYAREGLRILVMAKRTLNSADYTDWWARHQEIEMSLENRERRLRDSFAKLE 1032
            ....:..:||:.||.|||:|||.|..||:.::..::..|:...||...:::.:|.||.::...:|
Zfish   744 AAKRIAVRTQKDLDMYARDGLRTLCFAKKVISEQEFKAWFTSRQEALSAIDEKEERLMETANDIE 808

  Fly  1033 SNLTLLGATGIEDRLQDGVPETIASLLSAGISVWVLTGDKPETAINIAYSAKLFTQQMELIRLTA 1097
            :|||||||||||||||:.|||||.:|..||:.||||||||||||:|||||.||...:..:...|.
Zfish   809 NNLTLLGATGIEDRLQENVPETIQALRRAGMQVWVLTGDKPETAVNIAYSCKLLDHEDLVFTFTT 873

  Fly  1098 RSRDAAETAINFYLTDMENDKTTSTLGYGQSLR-----------KKQRALVVDGKTLTFILDPKS 1151
            ..:...:..:...|:::.  :|...||.....|           :....||:||.||...|  ..
Zfish   874 NKKSVCKMRLEDTLSEVR--RTWGGLGLDPQFRGYNSTFTGPLMEPSIGLVIDGPTLNMAL--SE 934

  Fly  1152 KLILPFLRLSKRCASVLCCRSTPLQKAYLVKVVKEELNLRTLAIGDGANDVSMIQMADVGVGISG 1216
            .|:..|:.|.|.|.:|||||.|||||:.:|||::::|.:.|||:|||||||:|||.||||:|:||
Zfish   935 DLVEQFVELCKHCRAVLCCRVTPLQKSSVVKVIRQKLRVMTLAVGDGANDVNMIQAADVGIGVSG 999

  Fly  1217 QEGMQAVMAADFTLPRFRYLERLLLAHGYWCYDRLSRMILYFFYKNAAFVFLIFWYQLYCGFSGQ 1281
            |||||||||:||.:.||::|:||||.||:|||.||:.|::||||||.|:|.|:||||.:|||||.
Zfish  1000 QEGMQAVMASDFAITRFKHLQRLLLVHGHWCYSRLANMVIYFFYKNVAYVNLLFWYQFFCGFSGT 1064

  Fly  1282 VMMDQMYLMLYNLIFTSLPPLAIGVYDKRVAEDLLLKNPYLYKNGRLGVAYRPHDFWLILLDALY 1346
            .|:|...::.:||.|||.||:..|:.||.|::..||..|.||:.|:....||...||:.:|||.|
Zfish  1065 AMIDYWLMIFFNLFFTSAPPIMFGIMDKEVSDSTLLSLPELYRRGQHSEGYRRSTFWIAILDAFY 1129

  Fly  1347 QSLVIFFVALCAYAESDVGIWEFGTTITASCLFANLVHCAIEIRSWTVLHVLSIVLSLGSFYLFA 1411
            ||||.||:....|.:||:||:.|||.:....||..::|.||||:||||:|.:.:|.|:..:::..
Zfish  1130 QSLVCFFIPYWTYNDSDIGIFSFGTPMNTVSLFTIILHLAIEIKSWTVVHWVIMVGSVLVYFILT 1194

  Fly  1412 IVYDSVCMNCFGVRSSYWVIFVCFASAVHWLVIMLSTVVAVLPRLLLTTVRISLCP 1467
            :.|.::|::|......||::....|..:.:||.:|:||||:|||..|..::.:|.|
Zfish  1195 LAYSAICISCNPPSDPYWIMHKQMADPMFYLVCVLTTVVALLPRYTLRVLKGTLAP 1250

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33298	NP_995666.1	P-type_ATPase_APLT_Dnf-like	252..1355	CDD:319770	477/1195 (40%)
atp10b	XP_017214606.1	P-type_ATPase_APLT_Dnf-like	48..1138	CDD:319770	477/1195 (40%)
		Haloacid Dehalogenase-like Hydrolases	<387..>500	CDD:473868	41/114 (36%)