Protein Alignment CG33298 and atp8b4

DIOPT Version :10

• Sequence 1: NP_995666.1
• Gene: CG33298 / 2768929
• FlyBaseID: FBgn0032120
• Length: 1517
• Species: Drosophila melanogaster
• Sequence 2: XP_002936618.2
• Gene: atp8b4 / 100145017
• XenbaseID: XB-GENE-5831431
• Length: 1188
• Species: Xenopus tropicalis
• Alignment Length: 1324
• Identity: 422/1324 - (31%)
• Similarity: 662/1324 - (50%)
• Gaps: 242/1324 - (18%)

  Fly   239 KTPKRDHPNGQF--VGNKIRTTKYTLLSFIPKNLLEQFHRVANLYFIFIVLLNWVPEISAFGKEV 301
            |...||: |.:|  ..|.|:|:||.:::|:|.||.|||.||||.||:|:::|..:||||:.....
 Frog    16 KANDRDY-NEKFNYANNAIKTSKYNIVTFLPINLFEQFQRVANAYFLFLLILQLIPEISSLSWFT 79

  Fly   302 AMIPVLFVLGVTAVKDLFEDRRRRASDKRINNTTCRVYDGETERYKKVKWQELRVGDIVHLSNNE 366
            .::|::.||.:|||||..:|..|..:|.::||...:|.  .:.:.:..||..:|.|||:.|.||:
 Frog    80 TIVPLVLVLTITAVKDATDDFFRHKTDNQVNNRQSQVL--LSGKLQNEKWMNVRAGDIIKLENNQ 142

  Fly   367 TVPADILLLRTSDPQGVCYIDTCDLDGETNLKRREVVRGFEEM-QSIFVPSKFVSRVEADAPTTK 430
            .|.||:|||.:|:|.|:||::|.:||||||||.|:.:....:: :||...:.|...|..:.|..|
 Frog   143 FVVADMLLLSSSEPHGLCYVETAELDGETNLKVRQALPVTADLGESITRLADFDGEVACEPPNNK 207

  Fly   431 LYRFHGALIHPTGERVPISTECLLLRESRLKNTDYIEGIVVYAGHETKSMLNNSGPRYKRSQVEQ 495
            |.:|.|.||. ...:..::...:|||...::||::..|:|::||.:||.|.|:...::||:.:::
 Frog   208 LDKFTGTLIW-KDNKYSLTNSKILLRGCVVRNTEWCFGMVIFAGPDTKLMQNSGKTKFKRTSIDR 271

  Fly   496 QMNIDVIWCVIILLILCVVGAIGCRMWLSSF-THFPVPYLPPNKL--TANMESMWIFWTYIVILQ 557
            .||..|:|....|:.:.::.|||..:|.... :.|.: ||..|::  ::.......||:||:||.
 Frog   272 LMNTLVLWIFGFLICMGIILAIGNSIWEHQVGSRFRI-YLYWNEVVNSSVFSGFLTFWSYIIILN 335

  Fly   558 VMIPLSLYVTIELCKILQVFHIHNNVDLFDAETNKQTECRAMNITEELGQIQHIFTDKTGTLTEN 622
            .::|:||||::|:.::...:.|:.:..:|.::.....|.|...:.||||||::||:|||||||:|
 Frog   336 TVVPISLYVSVEVIRLGHSYFINWDRKMFYSKRGTPAETRTTTLNEELGQIEYIFSDKTGTLTQN 400

  Fly   623 KMIFRRCVVNGSDYNHPPSELEKIYSKPGAPAP------PLIPNDNLNSDMAQLTQGTYL-TPHA 680
            .|.|.:|.|:|..|.....||.:........||      ||........|.: ||:...| .|:
 Frog   401 IMTFNKCSVSGKVYGELRDELGRKVGITEKTAPVDFSFNPLADRKFQFYDHS-LTEAIKLEEPY- 463

  Fly   681 QRIQEFLVVLAICNTVIVGAAPHRDMMNASGIIEVQQIGNSPANLKHGKQRQKLLASSTSTTTTT 745
              :||...:|::|:||:
 Frog   464 --VQEVFRLLSLCHTVM------------------------------------------------ 478

  Fly   746 TIINGPTTQPQVVSIPADRYIRLAESRSVTPSPPPNLLFALPAQSHQPTLSPISSSAESSPNSES 810
                                                                            |
 Frog   479 ----------------------------------------------------------------S 479

  Fly   811 ESPSPPMKNKSLSNSISPTGRAKAVINSKITSIATFLNAKTQGKRMKLPSSKTGTIYRTADGRPL 875
            |.                                                       :|| |..:
 Frog   480 EE-------------------------------------------------------KTA-GELV 488

  Fly   876 YEAESPDELALVNAAYSYDCCLLNRSPNQILVSMPMAGATREYEILKVLPFDSSRKCMSIVVRQI 940
            |:.:||||.|||.||.::.....:|:|..|.|.  ..|....|::|.:|.|::.||.||::||..
 Frog   489 YQVQSPDEGALVTAARNFGFIFKSRTPETITVE--EMGKVVTYQLLAILDFNNIRKRMSVIVRNP 551

  Fly   941 GSQEIVLYTKGADSSIMPVLVPCSHNSPEGILREQTQQLLDRYAREGLRILVMAKRTLNSADYTD 1005
            ..| :.||.||||:.:...|    |.|.|.:: ..|...|:.:|.||||.|.:|.:.| |.||..
 Frog   552 EGQ-VKLYCKGADTILFEKL----HESSEDLM-YITSDHLNEFAGEGLRTLALAYKDL-SEDYLK 609

  Fly  1006 WWAR-HQEIEMSLENRERRLRDSFAKLESNLTLLGATGIEDRLQDGVPETIASLLSAGISVWVLT 1069
            ||.: |.|...:|||||.||..::.::|||:.|||||.|||:||:||.|||:|||.|.|.||:||
 Frog   610 WWLKIHHEASTALENREERLAAAYEEIESNMMLLGATAIEDKLQEGVIETISSLLLANIKVWILT 674

  Fly  1070 GDKPETAINIAYSAKLFTQQME---------LIRLTARSRDAAETAI----NFY----LTDMEND 1117
            |||.|||:||.||..:.|..|.         ::.:....|.|.|...    |.|    .::...|
 Frog   675 GDKQETAMNIGYSCHMLTDDMNEIFVISGHTVMEVREELRKAKECTFGQSRNLYNGHQFSEKMQD 739

  Fly  1118 KTTSTLGYGQSLRKKQRALVVDGKTLTFILDPKSKLILPFLRLSKRCASVLCCRSTPLQKAYLVK 1182
            ....|: |.::: ..:.|:|::|.:|...|:  :.:...||.::..|.:|:|||.||||||.:|:
 Frog   740 TKLDTV-YEETV-TGEYAMVINGHSLAHALE--ADMEKEFLEIACMCKTVICCRVTPLQKAQVVE 800

  Fly  1183 VVKEELNLRTLAIGDGANDVSMIQMADVGVGISGQEGMQAVMAADFTLPRFRYLERLLLAHGYWC 1247
            :||:.....||||||||||:|||:.|.:|||||||||||||:|:|::..:||||:||||.||.|.
 Frog   801 LVKKYKKAVTLAIGDGANDISMIKSAHIGVGISGQEGMQAVLASDYSFAQFRYLQRLLLVHGRWS 865

  Fly  1248 YDRLSRMILYFFYKNAAFVFLIFWYQLYCGFSGQVMMDQMYLMLYNLIFTSLPPLAIGVYDKRVA 1312
            |.|:.:.:.||||||.||..:.||:..:||||.|.:.||.::.|:|:::||||.||:|::|:.|.
 Frog   866 YFRMCKFLCYFFYKNFAFTLVHFWFGFFCGFSAQTVYDQWFITLFNIVYTSLPVLAMGLFDQDVN 930

  Fly  1313 EDLLLKNPYLYKNGRLGVAYRPHDFWLILLDALYQSLVIFFVALCAY---AESD----VGIWEFG 1370
            :...:....||:.|:|.:.:....|::.:...:|.|..:||:...|:   |..|    .....|.
 Frog   931 DQNCMDYTKLYEPGQLNLLFNKRRFFICIAHGIYTSFALFFIPFGAFFNTAGEDGKHIADYQSFA 995

  Fly  1371 TTITASCLFANLVHCAIEIRSWTVLHVLSIVLSLGSFY--LFAIVYDSVCMNCFGVRSSYWVIFV 1433
            .|:..|.:....|...::...||.::...|..||..::  |||:..|.:    |.:..|::. ||
 Frog   996 VTVATSLVIVVSVQIGLDTSYWTAINHFFIWGSLAVYFSILFAMHGDGI----FDIFPSHFP-FV 1055

  Fly  1434 -----CFASAVHWLVIMLSTVVAVLPRLLLTTVRISLCP--DDSTKVILQSKRERSRGEALLVTW 1491
                 ..:....||||.|:||:.|:|.|....::..|.|  .|..:.:.|:|:.|...|..:...
 Frog  1056 GNARNSLSQKSVWLVIFLTTVICVMPVLTFRFLKADLSPTLSDKVRYLQQAKKRRKPLENRMRRV 1120

  Fly  1492 SRSTSASSIYRITDYGSKNQIITT 1515
            .|::|..|.|..:......::||:
 Frog  1121 HRTSSRRSGYAFSHQEGYGELITS 1144

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33298	NP_995666.1	P-type_ATPase_APLT_Dnf-like	252..1355	CDD:319770	374/1131 (33%)
atp8b4	XP_002936618.2	P-type_ATPase_APLT_Dnf-like	30..973	CDD:319770	374/1131 (33%)