Protein Alignment CG33310 and GABA-B-R1

DIOPT Version :10

• Sequence 1: NP_995718.2
• Gene: CG33310 / 2768910
• FlyBaseID: FBgn0053310
• Length: 876
• Species: Drosophila melanogaster
• Sequence 2: NP_523569.3
• Gene: GABA-B-R1 / 34878
• FlyBaseID: FBgn0260446
• Length: 841
• Species: Drosophila melanogaster
• Alignment Length: 256
• Identity: 53/256 - (20%)
• Similarity: 85/256 - (33%)
• Gaps: 88/256 - (34%)

  Fly   604 W-LYTLVFSVLYILFVIIFSMAWFDFIKDDASRKVPMIKMAQPFISFTPIGPRTNPKAVSFD--P 665
            | |||:|..:|.|..||:.|...||          |:.:..:.|       |..:|.:.:.|  .
  Fly   579 WKLYTMVSGLLSIDLVILLSWQIFD----------PLQRYLETF-------PLEDPVSTTDDIKI 626

  Fly   666 RNSTEVMEKYAGIMALLEKYGDYGHNPRFGTCTANEKFGYPSGEPCVFLKVNRIIGFKTEPYINS 730
            |...|..|.....|.|...||..|....||...|.|...         :||.:|   ....|:..
  Fly   627 RPELEHCESQRNSMWLGLVYGFKGLILVFGLFLAYETRS---------IKVKQI---NDSRYVGM 679

  Fly   731 DE-------LVKAKIDEV---------EFTAL---------------KRLLENTTTEEGHLNRTW 764
            ..       |:.|.:..|         .|.||               .:::|
  Fly   680 SIYNVVVLCLITAPVGMVIASQQDASFAFVALAVIFCCFLSMLLIFVPKVIE------------- 731

  Fly   765 ITCRSDKDKNVLIEFHPEPAIRTEYTDIEEKIEYIANEGKKSFFGPNDVNRIVALKIKNLK 825
             ..|..||| ...:::|:.||..|   .||:.:.:..|.:       ::.|::..|.:.::
  Fly   732 -VIRHPKDK-AESKYNPDSAISKE---DEERYQKLVTENE-------ELQRLITQKEEKIR 780

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33310	NP_995718.2	Na_K-ATPase	<703..846	CDD:471796	24/154 (16%)
GABA-B-R1	NP_523569.3	PBP1_GABAb_receptor	34..443	CDD:380589
		7tmC_GABA-B-R1	463..734	CDD:320418	40/197 (20%)
		TM helix 1	463..488	CDD:320418
		TM helix 2	500..521	CDD:320418
		TM helix 3	537..561	CDD:320418
		TM helix 4	581..601	CDD:320418	9/19 (47%)
		TM helix 5	638..664	CDD:320418	9/25 (36%)
		TM helix 6	673..696	CDD:320418	3/22 (14%)
		TM helix 7	703..728	CDD:320418	3/24 (13%)