DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33225 and Hgf

DIOPT Version :9

Sequence 1:	NP_001286682.1	Gene:	CG33225 / 2768860	FlyBaseID:	FBgn0053225	Length:	307	Species:	Drosophila melanogaster
Sequence 2:	NP_001276387.1	Gene:	Hgf / 15234	MGIID:	96079	Length:	728	Species:	Mus musculus

Alignment Length:	269	Identity:	69/269 - (25%)
Similarity:	114/269 - (42%)	Gaps:	53/269 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    45 CGTTRHPSRIRRVVGGNDADRFANPWMVMVLGENNVFCSGSLITRLFVLTSASCLLSLPK----- 104
            |..|:.    .|||.|........ |||.:...|...|.||||...:|||:..|..:..|
Mouse   488 CAKTKQ----LRVVNGIPTQTTVG-WMVSLKYRNKHICGGSLIKESWVLTARQCFPARNKDLKDY 547

  Fly   105 QVILGEYDRNCTSADCTSIRQVIDIDQKIIHGQFGLETVKKYDIALLRLAKKVSISDYVRPICLS 169
            :..||.:|.:....:  ..:|:::|.| :::|..|      .|:.||:||:...:.::|..|.|.
Mouse   548 EAWLGIHDVHERGEE--KRKQILNISQ-LVYGPEG------SDLVLLKLARPAILDNFVSTIDLP 603

  Fly   170 VDRQVGRSVQHFTAT---GWGTTEWNEPSTILQTVTLSKINRKYC----KGRLRQNIDASQLCVG 227
               ..|.::...|..   |||.|.......:|:...|..:..:.|    :|::  .::.|:||.|
Mouse   604 ---SYGCTIPEKTTCSIYGWGYTGLINADGLLRVAHLYIMGNEKCSQHHQGKV--TLNESELCAG 663

  Fly   228 ------GPRKDTCSGDAGGPLSLTLKIDGDGKWNNKSRAFLIGIV--SYGSSSCSGIGVYTNVEH 284
                  ||    |.||.||||...         .:|.| .::|::  ..|.:..:..|::..|.:
Mouse   664 AEKIGSGP----CEGDYGGPLICE---------QHKMR-MVLGVIVPGRGCAIPNRPGIFVRVAY 714

  Fly   285 YMDWIVRTI 293
            |..||.:.|
Mouse   715 YAKWIHKVI 723

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33225	NP_001286682.1	Tryp_SPc	56..289	CDD:214473	64/252 (25%)
CG33225	NP_001286682.1	Tryp_SPc	57..292	CDD:238113	65/254 (26%)
Hgf	NP_001276387.1	PAN_APPLE	41..123	CDD:238074
		KR	127..209	CDD:214527
		KR	211..289	CDD:214527
		KR	305..385	CDD:214527
		KR	389..471	CDD:238056
		Tryp_SPc	495..719	CDD:214473	64/252 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167833148
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930