Protein Alignment CG33225 and lrp2b

DIOPT Version :9

• Sequence 1: NP_001286682.1
• Gene: CG33225 / 2768860
• FlyBaseID: FBgn0053225
• Length: 307
• Species: Drosophila melanogaster
• Sequence 2: XP_021335953.1
• Gene: lrp2b / 101886177
• ZFINID: ZDB-GENE-111115-1
• Length: 4577
• Species: Danio rerio
• Alignment Length: 279
• Identity: 50/279 - (17%)
• Similarity: 99/279 - (35%)
• Gaps: 115/279 - (41%)

  Fly   111 YDRNCTSADCT------SIRQVIDIDQKIIHGQFGLETVKK----YDIALLRLAKKVSISDYVRP 165
            |.||.|:...:      .:..|:.:|         .:|.:|    .|:..||: :::::....|.
Zfish  3176 YIRNLTAVGSSMSVVLQGLTNVVALD---------FDTTEKRLYWVDVGTLRI-ERINLDGTGRE 3230

  Fly   166 IC----------LSVDRQVGRSVQHFTATGWGTTEWNEPSTILQTVTLSKINRKYCKGRLRQNID 220
            :.          |:|| .|||.:....||             ::.:.:|:::.:|.|..|:..:|
Zfish  3231 VIMQNDLGGAEGLAVD-WVGRKLYWADAT-------------MKAIHVSELDGRYRKKLLKDCVD 3281

  Fly   221 A-SQLCVGGPR-----------------KDTCSGDAG---------------GPLSLTL-----K 247
            . |..|...|:                 :....|.||               .|.:||:     |
Zfish  3282 TNSTYCFASPQAVAVNPKYGWLYWTDWGRKAFIGRAGMDGTQASALITTKLVWPHALTIDYTNNK 3346

  Fly   248 I-------------DGDGKWNNKSRAFLIGIVSYGSSSCSGIGVYTNVEHYMDWIVRTINK---- 295
            |             |.||:  |:.|| :.|.:.:..:    :.::.::.::.||...||.:
Zfish  3347 IFFADAHLNFLDYADMDGQ--NRHRA-ITGSLPHAYA----LTLFEDLVYWTDWNTHTIERAHKY 3404

  Fly   296 ---------SNTEKIANVH 305
                     :||.:..::|
Zfish  3405 TGANRVVMGNNTHRPNDIH 3423

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33225	NP_001286682.1	Tryp_SPc	56..289	CDD:214473	44/248 (18%)
		Tryp_SPc	57..292	CDD:238113	45/251 (18%)
lrp2b	XP_021335953.1	LDLa	2..34	CDD:238060
		LDLa	38..71	CDD:197566
		LDLa	80..114	CDD:238060
		LDLa	123..151	CDD:238060
		LDLa	155..189	CDD:238060
		LDLa	194..228	CDD:238060
		LDLa	235..269	CDD:238060
		FXa_inhibition	324..>347	CDD:317114
		LY	429..469	CDD:214531
		LY	471..516	CDD:214531
		LY	519..559	CDD:214531
		FXa_inhibition	631..672	CDD:317114
		Ldl_recept_b	808..848	CDD:278487
		LY	834..874	CDD:214531
		FXa_inhibition	950..982	CDD:317114
		LDLa	995..1029	CDD:238060
		LDLa	1036..1070	CDD:238060
		LDLa	1078..1112	CDD:238060
		LDLa	1119..1153	CDD:238060
		LDLa	1157..1192	CDD:238060
		LDLa	1200..1234	CDD:238060
		LDLa	1241..1275	CDD:238060
		LDLa	1282..1314	CDD:197566
		FXa_inhibition	1323..1358	CDD:317114
		EGF_CA	1360..1398	CDD:214542
		YncE	1388..>1660	CDD:331368
		LY	1470..1512	CDD:214531
		Ldl_recept_b	1535..1575	CDD:278487
		LY	1559..1601	CDD:214531
		LY	1789..1824	CDD:214531
		LY	1837..1879	CDD:214531
		LY	1922..1958	CDD:214531
		FXa_inhibition	1991..2027	CDD:317114
		Ldl_recept_b	2170..2210	CDD:278487
		LY	2195..2236	CDD:214531
		LY	2427..2468	CDD:214531
		LY	2468..2510	CDD:214531
		LY	2513..2553	CDD:214531
		FXa_inhibition	2623..2660	CDD:317114
		LDLa	2667..2699	CDD:197566
		LDLa	2709..2743	CDD:238060
		LDLa	2750..2785	CDD:238060
		LDLa	2789..2822	CDD:197566
		LDLa	2831..2863	CDD:197566
		LDLa	2873..2905	CDD:197566
		LDLa	2915..2952	CDD:197566
		LDLa	2961..2995	CDD:238060
		LDLa	2999..3031	CDD:197566
		Ldl_recept_a	3042..3077	CDD:278486
		cEGF	3100..3123	CDD:315355
		vWFA	<3115..3158	CDD:320736
		LY	3189..3229	CDD:214531	7/49 (14%)
		LY	3230..3272	CDD:214531	9/55 (16%)
		Ldl_recept_b	3303..3341	CDD:278487	6/37 (16%)
		LY	3327..3367	CDD:214531	8/41 (20%)
		LY	3374..3409	CDD:214531	4/38 (11%)
		LDLa	3480..3512	CDD:197566
		LDLa	3521..3552	CDD:197566
		LDLa	3561..3593	CDD:197566
		LDLa	3602..3634	CDD:197566
		LDLa	3646..3682	CDD:238060
		LDLa	3689..3722	CDD:238060
		LDLa	3727..3761	CDD:238060
		LDLa	3766..3800	CDD:238060
LDLa	3810..3841	CDD:197566
LDLa	3854..3883	CDD:197566
LDLa	3896..3930	CDD:238060
EGF_CA	3975..4014	CDD:214542
LY	4107..4142	CDD:214531
LY	4143..4186	CDD:214531
LY	4187..4230	CDD:214531
FXa_inhibition	4306..>4324	CDD:317114

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910