Protein Alignment CG33459 and TMPRSS5

DIOPT Version :10

• Sequence 1: NP_995855.2
• Gene: CG33459 / 2768847
• FlyBaseID: FBgn0053459
• Length: 284
• Species: Drosophila melanogaster
• Sequence 2: NP_110397.2
• Gene: TMPRSS5 / 80975
• HGNCID: 14908
• Length: 457
• Species: Homo sapiens
• Alignment Length: 284
• Identity: 80/284 - (28%)
• Similarity: 116/284 - (40%)
• Gaps: 49/284 - (17%)

  Fly    15 NQLLYGLAVLLE-PNCGQIPFRMRIFGGMDAGLVSTPWMAFLHNHLQFLCGGSLITSEFVLTAAH 78
            |....|..|.|. ..||..|...||.||........||.|.:....:..||||::...:|:||||
Human   194 NNCTSGQVVSLRCSECGARPLASRIVGGQSVAPGRWPWQASVALGFRHTCGGSVLAPRWVVTAAH 258

  Fly    79 CVMPTPKNLTVRLGEYDWTR------QMDSINPKHRHREYMVTRIYTHPSYRS-IAAYDIALLKL 136
            |:.      :.||......|      ...::.|   |:..:|.||..||.|.: ...||:|||:|
Human   259 CMH------SFRLARLSSWRVHAGLVSHSAVRP---HQGALVERIIPHPLYSAQNHDYDVALLRL 314

  Fly   137 NQTVEYTVAIRPICLV-----LPENFHEWYWLVDSVEDFTLTGWGATKTEPV--SQVLQSANL-- 192
            ...:.::..:..:||.     .|:....|           ::|||.|.....  |.:||...:
Human   315 QTALNFSDTVGAVCLPAKEQHFPKGSRCW-----------VSGWGHTHPSHTYSSDMLQDTVVPL 368

  Fly   193 --TQIDRGTCHDRYGHSVDHTHICAG--SSKSFACVGDSGSPLAMKVVHNRRYIHAQVGIVS--R 251
              ||:...:|  .|..::....:|||  ..::.||.||||.||........|.    ||:||  |
Human   369 FSTQLCNSSC--VYSGALTPRMLCAGYLDGRADACQGDSGGPLVCPDGDTWRL----VGVVSWGR 427

  Fly   252 GPKNCDGVTVFTNVVSFTEWIFRT 275
            |....:...|:..|..|.:||..|
Human   428 GCAEPNHPGVYAKVAEFLDWIHDT 451

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33459	NP_995855.2	Tryp_SPc	37..272	CDD:214473	70/256 (27%)
TMPRSS5	NP_110397.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..21
		SRCR_2	116..213	CDD:464747	6/18 (33%)
		Tryp_SPc	217..448	CDD:214473	70/256 (27%)