Protein Alignment CG33459 and KLK2

DIOPT Version :10

• Sequence 1: NP_995855.2
• Gene: CG33459 / 2768847
• FlyBaseID: FBgn0053459
• Length: 284
• Species: Drosophila melanogaster
• Sequence 2: NP_005542.1
• Gene: KLK2 / 3817
• HGNCID: 6363
• Length: 261
• Species: Homo sapiens
• Alignment Length: 281
• Identity: 79/281 - (28%)
• Similarity: 123/281 - (43%)
• Gaps: 62/281 - (22%)

  Fly    21 LAVLLEPNC-GQIP-FRMRIFGGMDAGLVSTPWMAFLHNHLQFLCGGSLITSEFVLTAAHCVMPT 83
            |::.|...| |.:| .:.||.||.:....|.||...:::|....|||.|:..::|||||||:
Human     6 LSIALSVGCTGAVPLIQSRIVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCL--- 67

  Fly    84 PKNLTVRLGEYDWTRQMDSINPKHRHREYMVTRIYTHPSY-------RSI-----AAYDIALLKL 136
            .||..|.||.:      :...|:...:...|:..:.||.|       :|:     :::|:.||:|
Human    68 KKNSQVWLGRH------NLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRL 126

  Fly   137 NQTVEYTVAIRPICLVLPENFHEWYWLVDSVEDFTL------TGWGATKTE----PVSQVLQSAN 191
            ::..:.|..::  .|.||            .::..|      :|||:.:.|    |.|  ||..:
Human   127 SEPAKITDVVK--VLGLP------------TQEPALGTTCYASGWGSIEPEEFLRPRS--LQCVS 175

  Fly   192 LTQIDRGTCHDRYGHSVDHTHICAG--SSKSFACVGDSGSPLAMKVVHNRRYIHAQVGIVSRGPK 254
            |..:....|...|...|....:|||  :.....|.||||.||....|..        ||.|.||:
Human   176 LHLLSNDMCARAYSEKVTEFMLCAGLWTGGKDTCGGDSGGPLVCNGVLQ--------GITSWGPE 232

  Fly   255 NC---DGVTVFTNVVSFTEWI 272
            .|   :...|:|.||.:.:||
Human   233 PCALPEKPAVYTKVVHYRKWI 253

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33459	NP_995855.2	Tryp_SPc	37..272	CDD:214473	72/261 (28%)
KLK2	NP_005542.1	Tryp_SPc	25..256	CDD:238113	73/262 (28%)