Protein Alignment CG33459 and F10

DIOPT Version :10

• Sequence 1: NP_995855.2
• Gene: CG33459 / 2768847
• FlyBaseID: FBgn0053459
• Length: 284
• Species: Drosophila melanogaster
• Sequence 2: NP_000495.1
• Gene: F10 / 2159
• HGNCID: 3528
• Length: 488
• Species: Homo sapiens
• Alignment Length: 255
• Identity: 72/255 - (28%)
• Similarity: 114/255 - (44%)
• Gaps: 39/255 - (15%)

  Fly    37 RIFGGMDAGLVSTPWMAFLHN-HLQFLCGGSLITSEFVLTAAHCVMPTPKNLTVRLGEYDWTRQM 100
            ||.||.:......||.|.|.| ..:..|||::::..::||||||:... |...||:|:.: |.|.
Human   234 RIVGGQECKDGECPWQALLINEENEGFCGGTILSEFYILTAAHCLYQA-KRFKVRVGDRN-TEQE 296

  Fly   101 DSINPKHRHREYMVTRIYTHPSYRSIAAYDIALLKLNQTVEYTVAIRPICLVLPENFHEWYWLVD 165
            :.....|.....:....:|..:|    .:|||:|:|...:.:.:.:.|.|  |||  .:|
Human   297 EGGEAVHEVEVVIKHNRFTKETY----DFDIAVLRLKTPITFRMNVAPAC--LPE--RDW----- 348

  Fly   166 SVEDFTLT-------GWGATKTE-PVSQVLQSANLTQIDRGTCHDRYGHSVDHTHICAG--SSKS 220
             .|...:|       |:|.|..: ..|..|:...:..:||.:|.......:.....|||  :.:.
Human   349 -AESTLMTQKTGIVSGFGRTHEKGRQSTRLKMLEVPYVDRNSCKLSSSFIITQNMFCAGYDTKQE 412

  Fly   221 FACVGDSGSPLAMKVVHNRRY--IHAQVGIVSRGPKNC---DGVTVFTNVVSFTEWIFRT 275
            .||.||||.|      |..|:  .:...||||.| :.|   ....::|.|.:|.:||.|:
Human   413 DACQGDSGGP------HVTRFKDTYFVTGIVSWG-EGCARKGKYGIYTKVTAFLKWIDRS 465

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33459	NP_995855.2	Tryp_SPc	37..272	CDD:214473	69/250 (28%)
F10	NP_000495.1	GLA	25..85	CDD:214503
		EGF_CA	86..122	CDD:238011
		FXa_inhibition	129..164	CDD:464251
		O-glycosylated at one site	183..203
		Tryp_SPc	235..464	CDD:238113	70/251 (28%)
		O-glycosylated at one site	476..485