DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33458 and F10

DIOPT Version :9

Sequence 1:	NP_995854.2	Gene:	CG33458 / 2768846	FlyBaseID:	FBgn0053458	Length:	281	Species:	Drosophila melanogaster
Sequence 2:	NP_058839.1	Gene:	F10 / 29243	RGDID:	61850	Length:	482	Species:	Rattus norvegicus

Alignment Length:	258	Identity:	73/258 - (28%)
Similarity:	127/258 - (49%)	Gaps:	33/258 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    37 RITGGRDSPLMLNPWLAYLHINSKF--ICGGSLLNHWFVLTAAHCFRDKNAKVLVRLGENDASQK 99
            ||.||::......||.|.|..:.:.  .|||::||.:::||||||..... :..||:|:.:..|:
  Rat   231 RIVGGQECKRGECPWQALLFSDEETDGFCGGTILNEFYILTAAHCLHQAK-RFKVRVGDLNTEQE 294

  Fly   100 IDCNESECAAPHLEYMIMQKLIHPLYRTAHYYDIALAKLNRYVVYTDSIRPICLMLNPNW-QVYV 163
             |..|    ..|...||::.  :...|..:.:|||:.:|...:.:.:::.|.||. ..:| :..:
  Rat   295 -DGGE----MVHEVDMIIKH--NKFQRDTYDFDIAMLRLKTPITFRENVAPACLP-QKDWAEATL 351

  Fly   164 DTIRYFIITGWGATNASEVSDK-LQLTRIPQIDRFTCRYWFGYMVDRTHICAGESKHYVGK---- 223
            .|.:..|::|:|.|:......| |::..:|.:||.|||....:.:.:...|||    |..|
  Rat   352 MTQKTGIVSGFGRTHEKGRQSKVLKMMEVPYVDRNTCRLSTSFSITQNMFCAG----YDAKQEDA 412

  Fly   224 --GDSGGPLGSMVDYKYAKRFFQFGIVSH----LRQPFHGVSVFTNILSYSNWIHRTIITNSG 280
              ||||||..:    ::...:|..||||.    .|:..:|  ::|.:.::..||.|::....|
  Rat   413 CQGDSGGPHVT----RFKDTYFVTGIVSWGEGCARKGKYG--IYTKVTAFLKWIDRSMKARVG 469

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33458	NP_995854.2	Tryp_SPc	37..271	CDD:214473	69/247 (28%)
CG33458	NP_995854.2	Tryp_SPc	38..274	CDD:238113	70/249 (28%)
F10	NP_058839.1	GLA	23..84	CDD:214503
		EGF_CA	86..122	CDD:238011
		FXa_inhibition	129..164	CDD:405372
		Tryp_SPc	232..462	CDD:238113	70/248 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24278
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010