DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG33458 and F7

DIOPT Version :9

Sequence 1:	NP_995854.2	Gene:	CG33458 / 2768846	FlyBaseID:	FBgn0053458	Length:	281	Species:	Drosophila melanogaster
Sequence 2:	NP_034302.2	Gene:	F7 / 14068	MGIID:	109325	Length:	446	Species:	Mus musculus

Alignment Length:	291	Identity:	78/291 - (26%)
Similarity:	121/291 - (41%)	Gaps:	74/291 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 LEWDCG---------ISKYTYRITGGRDSPLMLNPWLAYLHINSKFICGGSLLNHWFVLTAAHCF 80
            :|:.||         .|....||.||...|....||.|.|.||...:||..||:..:::||||||
Mouse   172 VEYPCGRIPVVEKRNSSSRQGRIVGGNVCPKGECPWQAVLKINGLLLCGAVLLDARWIVTAAHCF 236

  Fly    81 RDKN--AKVLVRLGENDASQKIDCNE-----SECAAPHLEYMIMQKLIHPLYRTAHYYDIALAKL 138
            .:..  ..:.|.:||:|.|:| |.:|     ::...|  :..|..|:.|         ||||.:|
Mouse   237 DNIRYWGNITVVMGEHDFSEK-DGDEQVRRVTQVIMP--DKYIRGKINH---------DIALLRL 289

  Fly   139 NRYVVYTDSIRPICLMLNPNWQVYVDTIRYFIITGWG-ATNASEVSDKLQLTRIPQIDRFTC--- 199
            :|.|.:||.:.|:||......:..:..||:..::||| ..:....:.:|....:|::....|
Mouse   290 HRPVTFTDYVVPLCLPEKSFSENTLARIRFSRVSGWGQLLDRGATALELMSIEVPRLMTQDCLEH 354

  Fly   200 -------------RYWFGYMVDRTHICAGESKHYVGKGDSGGPLGSMVDYKYAKRFFQFGIVS-- 249
                         .:..|||......|         |||||||..:    .|...::..|:||
Mouse   355 AKHSSNTPKITENMFCAGYMDGTKDAC---------KGDSGGPHAT----HYHGTWYLTGVVSWG 406

  Fly   250 -------HLRQPFHGVSVFTNILSYSNWIHR 273
                   |       :.|:|.:..|.:|:.|
Mouse   407 EGCAAIGH-------IGVYTRVSQYIDWLVR 430

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33458	NP_995854.2	Tryp_SPc	37..271	CDD:214473	72/266 (27%)
CG33458	NP_995854.2	Tryp_SPc	38..274	CDD:238113	73/269 (27%)
F7	NP_034302.2	GLA	24..85	CDD:214503
		EGF_CA	87..123	CDD:238011
		FXa_inhibition	132..168	CDD:291342
		Tryp_SPc	193..427	CDD:214473	72/265 (27%)
		Tryp_SPc	194..431	CDD:238113	73/269 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24278
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100