DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33458 and LOC100004411

DIOPT Version :9

Sequence 1:	NP_995854.2	Gene:	CG33458 / 2768846	FlyBaseID:	FBgn0053458	Length:	281	Species:	Drosophila melanogaster
Sequence 2:	XP_001343728.4	Gene:	LOC100004411 / 100004411	-ID:	-	Length:	494	Species:	Danio rerio

Alignment Length:	265	Identity:	70/265 - (26%)
Similarity:	120/265 - (45%)	Gaps:	67/265 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    37 RITGGRDSPLMLNPWLAYLHINSKF-ICGGSLLNHWFVLTAAHCFRDKNAKVLVRLGENDASQKI 100
            ||.||:......:||...|....:: .|||||:|..:|:|||||.:.....:.:  |:.| ..:.
Zfish   248 RIVGGQLQRQGGSPWQVLLRREDEYGFCGGSLINQRWVITAAHCLQQTPHHITI--GDYD-KMRP 309

  Fly   101 DCNESECAAPHLEYMIMQKLI-HPLYRTAHYY----DIALAKLNRYVVYTDSIRPICL------- 153
            |.:|.:        :.::|:| ||.|   |.|    ||||..|:..|.......|.||
Zfish   310 DKDEQK--------ITVEKIIPHPHY---HEYTFDSDIALLYLSSAVTLGPFASPACLPDANLAE 363

  Fly   154 -MLNPNWQVYVDTIRYFIITGWGATNASEVSDK-LQLTRIPQIDRFTC-----------RYWFGY 205
             ::.|..|        .:::|||:|:..:.|.: |:..::|.:::.:|           .:..|:
Zfish   364 RLMKPGEQ--------GLVSGWGSTHYLQRSSRFLRKVQLPVVEQKSCINSTEQIITDNMFCAGF 420

  Fly   206 MVDRTHICAGESKHYVGKGDSGGPLGSMVDYKYAKRFFQFGIVSH----LRQPFHGVSVFTNILS 266
            :::....|.         ||||||.  :|:|:  ..:|..|:||.    ..|..:|  |:|.:.:
Zfish   421 LMEEMDACT---------GDSGGPF--IVNYR--GTWFLTGVVSWGERCASQGKYG--VYTRLGN 470

  Fly   267 YSNWI 271
            |.:||
Zfish   471 YLSWI 475

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33458	NP_995854.2	Tryp_SPc	37..271	CDD:214473	68/263 (26%)
CG33458	NP_995854.2	Tryp_SPc	38..274	CDD:238113	69/264 (26%)
LOC100004411	XP_001343728.4	GLA	22..85	CDD:214503
		EGF_CA	86..122	CDD:238011
		FXa_inhibition	128..164	CDD:291342
		Tryp_SPc	248..475	CDD:214473	68/263 (26%)
		Tryp_SPc	249..477	CDD:238113	69/264 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24278
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	2.010