DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sp212 and Prss46

DIOPT Version :9

Sequence 1:	NP_996209.2	Gene:	Sp212 / 2768666	FlyBaseID:	FBgn0053329	Length:	516	Species:	Drosophila melanogaster
Sequence 2:	NP_898926.2	Gene:	Prss46 / 74306	MGIID:	1921556	Length:	314	Species:	Mus musculus

Alignment Length:	288	Identity:	66/288 - (22%)
Similarity:	122/288 - (42%)	Gaps:	43/288 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   257 DPRSQISSVVCGREGSTTPF-----------------IVRGNEFPRGQYPWLSAVYHKEVRALAF 304
            ||...:||.:.....::.|:                 :|.|.....|::||..::....:    :
Mouse     7 DPHGLLSSPLASARLNSLPYMEGPWIWSCGQTNITCKVVNGKAVEVGKWPWQVSILFLGM----Y 67

  Fly   305 KCRGSLISSSIVISAAHCVHRMTED-RVVVGLGRYDLDDYGEDGAEMRNVMRLLWHPDYNTRSYS 368
            .|.||||....:::||||:.|.... :..|.:|...|.|  ...:|:. |.|::.|.::..| .|
Mouse    68 ICSGSLIHHHWILTAAHCLQRSKNPAKYTVKVGVQTLPD--NSTSELL-VTRIVIHENFINR-MS 128

  Fly   369 DADIALITIERPVTFNDIIAPICMWTVEASRTVSTTGFIAGWGRDEDSSRTQYPRVVE---AEIA 430
            | |||::.::.|||::.::.|||:.:.....::.|..::.|||.::.....:.|..|:   ..|.
Mouse   129 D-DIAILKLKYPVTWSPLVQPICLPSFNLKPSIGTMCWVVGWGLEKAEGHPKTPYSVQGLAVRIV 192

  Fly   431 SPTVCASTWRGTMVTERS-------LCAGNRDGSGPCVGDSGGGLMVKQGDRWLLRGIVSAGERG 488
            :..:|...::..::..:.       ||..:..|...|...||..|:.:....|:..|:||..
Mouse   193 NNEICNHRYQFLLLKNQKKFIGNDMLCTSSEWGLDTCQDTSGSSLVCQMNKTWVQMGVVSWN--- 254

  Fly   489 PAGTCQLNQY-VLYCDLSKHINWISENI 515
              ..|...|: .:|...|....||...|
Mouse   255 --FDCGRRQFPSVYTSTSHFTQWIKRQI 280

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sp212	NP_996209.2	GD_N	23..122	CDD:292649
		Tryp_SPc	277..514	CDD:238113	60/248 (24%)
		Tryp_SPc	277..511	CDD:214473	58/245 (24%)
Prss46	NP_898926.2	Tryp_SPc	43..276	CDD:214473	58/246 (24%)
Prss46	NP_898926.2	Tryp_SPc	44..279	CDD:238113	60/248 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910