DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sp212 and Hgfac

DIOPT Version :9

Sequence 1:	NP_996209.2	Gene:	Sp212 / 2768666	FlyBaseID:	FBgn0053329	Length:	516	Species:	Drosophila melanogaster
Sequence 2:	NP_445772.1	Gene:	Hgfac / 58947	RGDID:	70909	Length:	653	Species:	Rattus norvegicus

Alignment Length:	298	Identity:	86/298 - (28%)
Similarity:	134/298 - (44%)	Gaps:	49/298 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   240 PPAVVTVPPATPPPQRFDPRSQISSVVCGREGSTTPF----IVRGNEFPRGQYPWLSAVYHKEVR 300
            |..:.|:|.:|          ..:...||:......|    |:.|:....|.:|||:|:|...
  Rat   375 PEVLATLPEST----------STARPTCGKRHKKRTFLRPRIIGGSSSLPGSHPWLAAIYIGN-- 427

  Fly   301 ALAFKCRGSLISSSIVISAAHCVHRM-TEDRVVVGLGRYDLD---DYGEDGAEMRNVMRLLWHPD 361
              .| |.|||:.:..|:|||||.... ..|.:.|.||::..:   |..:..|..:.|...|
  Rat   428 --GF-CAGSLVHTCWVVSAAHCFSSSPPRDSITVVLGQHFFNRTTDVTQTFAIEKYVPYTL---- 485

  Fly   362 YNTRSYSDADIALITI----ERPVTFNDIIAPICMWTVEASRTVSTTGFIAGWGR-DEDSS---- 417
            |:..:.:|.|:.||.:    ||....:..:.|||:....:|........|||||. ||:.|
  Rat   486 YSVFNPNDHDLVLIRLKKKGERCAVRSQFVQPICLPEAGSSFPTGHKCQIAGWGHMDENVSGYSN 550

  Fly   418 ---RTQYPRVVEAEIASPTVCASTWRGTMVTERSLCAGNRD-GSGPCVGDSGGGLMVKQGDRWLL 478
               ....|.|.:.:.:||.|     .|..::...||||..| .|..|.|||||.|:.::.....|
  Rat   551 SLLEALVPLVADHKCSSPEV-----YGADISPNMLCAGYFDCKSDACQGDSGGPLVCEKNGVAYL 610

  Fly   479 RGIVSAGERGPAGTCQLNQYVLYCDLSKHINWISENIR 516
            .||:|.|:    |..:||:..:|..:|.:::||::.||
  Rat   611 YGIISWGD----GCGRLNKPGVYTRVSNYVDWINDRIR 644

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sp212	NP_996209.2	GD_N	23..122	CDD:292649
		Tryp_SPc	277..514	CDD:238113	77/253 (30%)
		Tryp_SPc	277..511	CDD:214473	75/250 (30%)
Hgfac	NP_445772.1	FN2	99..145	CDD:128373
		EGF_CA	159..194	CDD:238011
		FN1	197..237	CDD:238018
		EGF	242..274	CDD:278437
		Kringle	283..364	CDD:278480
		Tryp_SPc	405..639	CDD:214473	75/251 (30%)
		Tryp_SPc	406..641	CDD:238113	77/252 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910