Protein Alignment Sp212 and Hgfac

DIOPT Version :10

• Sequence 1: NP_996209.2
• Gene: Sp212 / 2768666
• FlyBaseID: FBgn0053329
• Length: 516
• Species: Drosophila melanogaster
• Sequence 2: NP_445772.1
• Gene: Hgfac / 58947
• RGDID: 70909
• Length: 653
• Species: Rattus norvegicus
• Alignment Length: 298
• Identity: 86/298 - (28%)
• Similarity: 134/298 - (44%)
• Gaps: 49/298 - (16%)

  Fly   240 PPAVVTVPPATPPPQRFDPRSQISSVVCGREGSTTPF----IVRGNEFPRGQYPWLSAVYHKEVR 300
            |..:.|:|.:|          ..:...||:......|    |:.|:....|.:|||:|:|...
  Rat   375 PEVLATLPEST----------STARPTCGKRHKKRTFLRPRIIGGSSSLPGSHPWLAAIYIGN-- 427

  Fly   301 ALAFKCRGSLISSSIVISAAHCVHRM-TEDRVVVGLGRYDLD---DYGEDGAEMRNVMRLLWHPD 361
              .| |.|||:.:..|:|||||.... ..|.:.|.||::..:   |..:..|..:.|...|
  Rat   428 --GF-CAGSLVHTCWVVSAAHCFSSSPPRDSITVVLGQHFFNRTTDVTQTFAIEKYVPYTL---- 485

  Fly   362 YNTRSYSDADIALITI----ERPVTFNDIIAPICMWTVEASRTVSTTGFIAGWGR-DEDSS---- 417
            |:..:.:|.|:.||.:    ||....:..:.|||:....:|........|||||. ||:.|
  Rat   486 YSVFNPNDHDLVLIRLKKKGERCAVRSQFVQPICLPEAGSSFPTGHKCQIAGWGHMDENVSGYSN 550

  Fly   418 ---RTQYPRVVEAEIASPTVCASTWRGTMVTERSLCAGNRD-GSGPCVGDSGGGLMVKQGDRWLL 478
               ....|.|.:.:.:||.|     .|..::...||||..| .|..|.|||||.|:.::.....|
  Rat   551 SLLEALVPLVADHKCSSPEV-----YGADISPNMLCAGYFDCKSDACQGDSGGPLVCEKNGVAYL 610

  Fly   479 RGIVSAGERGPAGTCQLNQYVLYCDLSKHINWISENIR 516
            .||:|.|:    |..:||:..:|..:|.:::||::.||
  Rat   611 YGIISWGD----GCGRLNKPGVYTRVSNYVDWINDRIR 644

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sp212	NP_996209.2	GD_N	23..127	CDD:464985
		Tryp_SPc	277..514	CDD:238113	77/253 (30%)
Hgfac	NP_445772.1	FN2	99..145	CDD:128373
		EGF_CA	159..194	CDD:238011
		FN1	197..237	CDD:238018
		EGF	242..274	CDD:394967
		Kringle	283..364	CDD:395005
		Tryp_SPc	406..641	CDD:238113	77/252 (31%)