DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sp212 and proca

DIOPT Version :9

Sequence 1:	NP_996209.2	Gene:	Sp212 / 2768666	FlyBaseID:	FBgn0053329	Length:	516	Species:	Drosophila melanogaster
Sequence 2:	NP_956650.1	Gene:	proca / 393327	ZFINID:	ZDB-GENE-060824-5	Length:	434	Species:	Danio rerio

Alignment Length:	254	Identity:	80/254 - (31%)
Similarity:	130/254 - (51%)	Gaps:	30/254 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly   275 PFIVRGNEFPRGQYPWLSAVYHKEVRALAFKCRGSLISSSIVISAAHCVHRMTEDRVVVGLGRYD 339
            |:::.||...||:.||.:.:.:...|   |.|.|.||..:.|::||||:.  |..:..|.||.|.
Zfish   193 PWVMGGNVGKRGESPWQALILNHLGR---FHCGGVLIDENWVLTAAHCLE--TSSKFSVRLGDYQ 252

  Fly   340 LDDYGEDGAEMR-NVMRLLWHPDYNTRSYSDADIALITIERPVTFNDIIAPICMWTVEASRTV-- 401
            ...:  :|:|:. .|.:.:.||.||..:. |.||||:.::.||.|:..|.|.|:.::|.::.:
Zfish   253 RFKF--EGSEVTLPVKQHISHPQYNPITV-DNDIALLRLDGPVKFSTYILPACLPSLELAKRMLH 314

  Fly   402 --STTGFIAGWGRDEDSSRTQYP---RVVEAEIASPTVCASTWRGTMVTERSLCAG----NRDGS 457
              .|...|.|||::..|: |.|.   ..||..|.....|:......: ::..||||    .:|.
Zfish   315 RNGTVTIITGWGKNNQSA-TSYNSTLHYVELPIVDNKECSRHMMNNL-SDNMLCAGVLGQVKDA- 376

  Fly   458 GPCVGDSGGGLMVKQGDRWLLRGIVSAGERGPAGTCQLNQYVLYCDLSKHINWISENIR 516
              |.|||||.:|....|.|.|.|:||.||    |..|.::..:|..::.:::|| :::|
Zfish   377 --CEGDSGGPMMTLFHDTWFLVGLVSWGE----GCGQRDKLGIYTKVASYLDWI-DSVR 428

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sp212	NP_996209.2	GD_N	23..122	CDD:292649
		Tryp_SPc	277..514	CDD:238113	78/248 (31%)
		Tryp_SPc	277..511	CDD:214473	76/245 (31%)
proca	NP_956650.1	GLA	23..84	CDD:214503
		EGF_CA	85..119	CDD:238011
		FXa_inhibition	128..165	CDD:291342
		Tryp_SPc	195..427	CDD:238113	78/249 (31%)
		Tryp_SPc	197..424	CDD:214473	76/243 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910