DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sp212 and AgaP_AGAP012270

DIOPT Version :9

Sequence 1:	NP_996209.2	Gene:	Sp212 / 2768666	FlyBaseID:	FBgn0053329	Length:	516	Species:	Drosophila melanogaster
Sequence 2:	XP_320269.4	Gene:	AgaP_AGAP012270 / 1280418	VectorBaseID:	AGAP012270	Length:	862	Species:	Anopheles gambiae

Alignment Length:	265	Identity:	75/265 - (28%)
Similarity:	135/265 - (50%)	Gaps:	13/265 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly   262 ISSVVCGREGSTTPFIV-RGNEFPRGQYPWLSAVYHKEVRALAFKCRGSLISSSIVISAAHCV-- 323
            ::.:||||....:.::: .|.:...|.:||.:.:|.:...|..:||.||:|....::::.|||
Mosquito    24 VNRLVCGRRKVKSVYLIHNGIDAMPGHWPWHAVIYQRANGAEEYKCGGSIIDEDTILTSGHCVTV 88

  Fly   324 --HRMTEDRVVVGLGRYDLDDYGEDGAEMRNVMRLLWHPDYNTRSYSDADIALITIERPVTFNDI 386
              ..::.:::.:.:||..|.:..| ..:...|.:::.||..|.|.:.: |||||.:...:|....
Mosquito    89 GSRAISPEQLSIEVGRIRLHERTE-YTQTHGVRQVIVHPGLNVRRFKN-DIALIKLASNITMTPH 151

  Fly   387 IAPICMWTVEASR--TVSTTGFIAGWGRDEDSSRTQYPRVVEAEIASPTVCASTWR---GTMVTE 446
            :.|||:||::.::  .|...|.:.|:|..|....::..:.....:.....|.:..|   ||.:|.
Mosquito   152 VQPICLWTMDNNQELIVGKNGTVLGFGLTEQDVVSEQLKQASIGVVDTLTCLANDRAAFGTYLTS 216

  Fly   447 RSLCAGNRDGSGPCVGDSGGGLMVKQGDRWLLRGIVS-AGERGPAGTCQLNQYVLYCDLSKHINW 510
            ...|.|.|||...|.|||||||.::...||.:||||| ...|.....|..:::..:.|::|::.|
Mosquito   217 EMFCGGGRDGVSACNGDSGGGLFLEVEGRWFVRGIVSFIPLRKNTALCDTSKFTAFADVAKYLKW 281

  Fly   511 ISENI 515
            |.:.|
Mosquito   282 IEQYI 286

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sp212	NP_996209.2	GD_N	23..122	CDD:292649
		Tryp_SPc	277..514	CDD:238113	70/247 (28%)
		Tryp_SPc	277..511	CDD:214473	68/244 (28%)
AgaP_AGAP012270	XP_320269.4	Tryp_SPc	40..284	CDD:238113	70/245 (29%)
		Tryp_SPc	42..282	CDD:214473	68/241 (28%)
		Tryp_SPc	329..>443	CDD:304450
		Tryp_SPc	614..842	CDD:304450
		Tryp_SPc	614..839	CDD:214473
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	145	1.000	Domainoid score	I9368
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D294086at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm9620
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X174
TreeFam	0	0.000	Not matched by this tool.
	5	4.920