DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sp212 and AgaP_AGAP008808

DIOPT Version :9

Sequence 1:	NP_996209.2	Gene:	Sp212 / 2768666	FlyBaseID:	FBgn0053329	Length:	516	Species:	Drosophila melanogaster
Sequence 2:	XP_557970.3	Gene:	AgaP_AGAP008808 / 1275666	VectorBaseID:	AGAP008808	Length:	574	Species:	Anopheles gambiae

Alignment Length:	267	Identity:	80/267 - (29%)
Similarity:	143/267 - (53%)	Gaps:	23/267 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly   265 VVCGREGSTTPFIV-RGNEFPRGQYPWLSAVYHKEVRALAFKCRGSLISSSIVISAAHCVHR--- 325
            :.|||....:.|:: .|.:...|.:||.:|::|...|...::|.||::..:.:::|:|||:.
Mosquito    31 LTCGRRKVQSVFLIHNGVDAKAGHWPWHAAIFHGNGRQEEYQCGGSILDQNTILTASHCVYTHKS 95

  Fly   326 -MTEDRVVVGLGRYDLDDYGEDGAEMRNVMRLLWHPDYNTRSYSDADIALITIERPVTFNDIIAP 389
             ::..||.|.:|:..|.:..| ..::..|..::.||::|:.|::: ||||:.:...:|....:.|
Mosquito    96 VISAARVSVHVGQIHLKETSE-YTQIHGVQDIILHPEFNSNSFNN-DIALLKLSTNITMTKYVQP 158

  Fly   390 ICMWTVEASR--TVSTTGFIAGWGRDE-----DSSRTQYPRVVEAEIASPTVCASTWR---GTMV 444
            :|:||:::::  .|...|.|.|:|.:|     |..:.....||:|     ..|..:.|   |.::
Mosquito   159 VCLWTMDSNQEMIVGKNGTIVGFGLNEHDVVSDQLKQALVGVVDA-----LTCIKSDRAAFGPVL 218

  Fly   445 TERSLCAGNRDGSGPCVGDSGGGLMVKQGDRWLLRGIVS-AGERGPAGTCQLNQYVLYCDLSKHI 508
            |....|...|.|.|.|.||||||:..:.|.:|.:||:|| ...||..|.|...:|..|.|::|::
Mosquito   219 TSEMFCGKGRTGVGACNGDSGGGMFFEVGGKWFVRGLVSFTPLRGNTGLCDPLKYTAYTDVAKYL 283

  Fly   509 NWISENI 515
            .||.:.|
Mosquito   284 EWIKQYI 290

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sp212	NP_996209.2	GD_N	23..122	CDD:292649
		Tryp_SPc	277..514	CDD:238113	75/252 (30%)
		Tryp_SPc	277..511	CDD:214473	73/249 (29%)
AgaP_AGAP008808	XP_557970.3	Tryp_SPc	44..288	CDD:238113	75/250 (30%)
		Tryp_SPc	46..286	CDD:214473	73/246 (30%)
		Tryp_SPc	324..566	CDD:304450
		Tryp_SPc	330..566	CDD:214473
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	145	1.000	Domainoid score	I9368
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D294086at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm9620
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X174
TreeFam	0	0.000	Not matched by this tool.
	5	4.920