DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sp212 and AgaP_AGAP010662

DIOPT Version :9

Sequence 1:	NP_996209.2	Gene:	Sp212 / 2768666	FlyBaseID:	FBgn0053329	Length:	516	Species:	Drosophila melanogaster
Sequence 2:	XP_311382.4	Gene:	AgaP_AGAP010662 / 1272470	VectorBaseID:	AGAP010662	Length:	584	Species:	Anopheles gambiae

Alignment Length:	265	Identity:	81/265 - (30%)
Similarity:	142/265 - (53%)	Gaps:	18/265 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly   267 CGREGSTTPFIVRGNEFPR-GQYPWLSAVYHKEVRALAFK--CRGSLISSSIVISAAHCVHRMTE 328
            ||........:|:|....: |.:||.:|:||:.:.:..|:  |.||::...:|::|||||...|.
Mosquito    29 CGERMVKRKGLVKGGYSTQPGDWPWHAALYHRGINSAGFEYACGGSIVHRYLVLTAAHCVTLATS 93

  Fly   329 DRVV------VGLGRYDLDDYGEDGAEMRNVMRLLWHPDYNTRSYSDADIALITIERPVTFNDII 387
            .|.:      :.|||::|.:..|:.||..:|:..:.|..|...::.: |||::.:|.|:.|||.|
Mosquito    94 RRKIPAENMQLRLGRFNLMNNEEEYAEEFDVIETIMHEGYRPTTFEN-DIAILRVEIPIIFNDYI 157

  Fly   388 APICMWTVEASRTV----STTGFIAGWGRDEDSSRTQYPRVVEAEIASPTVCASTWR---GTMVT 445
            .|:|:|..:....:    :..|.:.|||..||:............:.....|.::.|   |..:.
Mosquito   158 QPVCLWKRDDGVVLPWFYNQPGTVVGWGLSEDNMIGTTLNEARMPVVDSWTCLASDRAFFGKFLQ 222

  Fly   446 ERSLCAGNRDGSGPCVGDSGGGLMVKQGDRWLLRGIVS-AGERGPAGTCQLNQYVLYCDLSKHIN 509
            .::.|||.::|:|.|.||||||:..:..:||.|:|:|| :.....:|.|.|.||:.:.|.|::|:
Mosquito   223 SKAFCAGYKNGTGVCNGDSGGGMFFQFQNRWYLKGVVSFSNTNDYSGVCNLKQYIGFTDASQYID 287

  Fly   510 WISEN 514
            |:.:|
Mosquito   288 WVYDN 292

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sp212	NP_996209.2	GD_N	23..122	CDD:292649
		Tryp_SPc	277..514	CDD:238113	78/253 (31%)
		Tryp_SPc	277..511	CDD:214473	77/250 (31%)
AgaP_AGAP010662	XP_311382.4	Tryp_SPc	42..292	CDD:238113	77/250 (31%)
		Tryp_SPc	42..289	CDD:214473	76/247 (31%)
		Tryp_SPc	334..578	CDD:214473
		Tryp_SPc	334..578	CDD:304450
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	145	1.000	Domainoid score	I9368
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D294086at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm9620
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X174
TreeFam	0	0.000	Not matched by this tool.
	5	4.920