Protein Alignment: GLRA2 and ort

• Sequence 1: NP_001112357.1
• Gene: GLRA2
• HGNCID: 4327
• Length: 452
• Species: Homo sapiens
• Sequence 2: NP_524406.1
• Gene: ort
• FlyBaseID: FBgn0003011
• Length: 485
• Species: Drosophila melanogaster
• Alignment Length: 477
• Identity: 158/478 (33%)
• Similarity: 240/478 (50%)
• Gaps: 71/478 (15%)

Human    27 CKDHDSRSGKQPSQTLSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSVTETTMD 91
            |..|.::...|  |:|:.:|.|.:.:.|   ||....|..:|.|..|..::.:....|:.|.:|.
  Fly    14 CMKHYAKGEFQ--QSLAITDILPEDIKR---YDKMRPPKKEGQPTIVYFHVTVMGLDSIDENSMT 73

Human    92 YRVNIFLRQQWNDSRLAYSEYPDDSLD----LDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLL 152
            |..::|..|.|.|.||   ..|::...    |:...|.::|:||.||.|.|...|..:|..|..:
  Fly    74 YVADVFFAQTWKDHRL---RLPENMTQEYRLLEVDWLKNMWRPDSFFKNAKSVTFQTMTIPNHYM 135

Human   153 RISKNGKVLYSIRLTLTLSCPMDLKNFPMDVQTCTMQLESFGYTMNDLIFEWLSDGPVQVAEGLT 217
            .:.|:..:||.::|||.|||.|:...:|.|.|.|.:|:||..:|.:||||:|....|:.|.|.:.
  Fly   136 WLYKDKTILYMVKLTLKLSCIMNFAIYPHDTQECKLQMESLSHTTDDLIFQWDPTTPLVVDENIE 200

Human   218 LPQFILKEEKELGYCTKHYNTGKFTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDA 282
            |||..| ...|...||:.|:||.|||:||.|.|:|::.||:...|||:.:|||:|||||||..:|
  Fly   201 LPQVAL-IRNETADCTQVYSTGNFTCLEVVFTLKRRLVYYVFNTYIPTCMIVIMSWVSFWIKPEA 264

Human   283 APARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAAVNFV------ 341
            |||||.||:|::||::||.:.|::|||.|||:||:|.:|:||.:|||.||:||..:|.|
  Fly   265 APARVTLGVTSLLTLSTQHAKSQSSLPPVSYLKAVDAFMSVCTVFVFMALMEYCLINIVLSDTPI 329

Human   342 --------------------------------SRQHKEFLRL--RRRQKRQNKEEDVTRESRFNF 372
                                            |:|....|.|  .:.:|.:...:::|:..|...
  Fly   330 PKPMAYPPKPVAGDGPKKEGEGAPPGGSNSTASKQQATMLPLADEKIEKIEKIFDEMTKNRRIVT 394

Human   373 SGYGM--------GHCLQVKDGTAVKATPANPLPQPPK----DGDAIKKKFV---DRAKR---ID 419
            :...:        |..:..::...:......|.|.||:    :.:..|.|..   :|.||   ||
  Fly   395 TTRRVVRPPLDADGPWIPRQESRIILTPTIAPPPPPPQPAAPEPELPKPKLTPAQERLKRAIYID 459

Human   420 TISRAAFPLAFLIFNIFYWITY 441
            ..||..||..|...|..||..:
  Fly   460 RSSRVLFPALFASLNGIYWCVF 481

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GLRA2	NP_001112357.1	LIC	46..441	CDD:273305	153/457 (33%)
		Strychnine-binding. {ECO:0000250|UniProtKB:O93430}	236..241		3/5 (60%)
ort	NP_524406.1	LIC	31..481	CDD:273305	153/457 (33%)
		Neur_chan_LBD	38..235	CDD:280998	74/204 (36%)
		Neur_chan_memb	243..>334	CDD:280999	48/91 (53%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
eggNOG	1	0.900				E1_KOG3644
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010				D276914at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100			O	PTHR18945
Phylome	1	0.910		0.600	Consistency score
RoundUp	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.920