DRSC/TRiP Functional Genomics Resources

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Protein Alignment: GLRA2 and NtR

Sequence 1:NP_001112357.1 Gene:GLRA2 HGNCID:4327 Length:452 Species:Homo sapiens
Sequence 2:NP_651958.2 Gene:NtR FlyBaseID:FBgn0029147 Length:585 Species:Drosophila melanogaster

Alignment Length:312 Identity:67/313 (21%)
Similarity:115/313 (37%) Gaps:81/313 (26%)


Human    57 GYDARIRP---------------NFKGPPVNVTCNIFINSFGSVT------ETTMDYRVNIFLRQ 100
            ||.:.|.|               |.:....::..|:...||...|      :|:...:..:.:..
  Fly   201 GYGSEIAPIVKEETKTEKLLSHLNIQAENASMPANLSSISFHFQTRSLAYEQTSSLLQTRMHMMM 265

Human   101 QWNDSRLAYSEYPDDSLDLD----PSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKV- 160
            .|.||||.:.  |:|...|:    |.:  .||||.:...|....:...|....:|: :..||.: 
  Fly   266 HWRDSRLVWK--PEDFGSLESFEHPDL--RIWKPHMNVLNGALQSMGQVLQSYELM-VYANGSIT 325

Human   161 LYSIRLTLTLSCPMDLKNFPMDVQTCTMQLESFGYTMNDLIFEWLSD--GPVQVAEGLTLP---- 219
            ||:..|.|...|....:|:|.:..||.::|...|....:.:.....|  .|:...|.:..|    
  Fly   326 LYAQNLQLASWCVDSARNWPSERVTCDIELGLNGQEGQENVALIYDDQRKPIAPNEHVNTPSGWS 390

Human   220 ----QFILKEEKELGYCTKHYN--------TGKFTCIEVKFHLERQMGYYLIQMYIP-------- 264
                ..:|.|...    .:.||        ||.   :.::|.|:|...:|:...|:|        
  Fly   391 FTQMSVVLVENDS----QRRYNPKGMMQKMTGD---VAIEFTLQRNRSFYMTVFYLPLIACQMFL 448

Human   265 ------------SLLIV---ILSWVSFWINMDAAPARVALGITT--VLTMTT 299
                        ||:::   |.:|...::...|:|..|...:|.  |:.|||
  Fly   449 ILSFVLRSTRRSSLILIALLIAAWGLMYMTRYASPHYVPPMMTAYKVIMMTT 500

Known Domains:


GeneSequenceDomainRegion External IDIdentity
GLRA2NP_001112357.1 LIC 46..441 CDD:273305 67/313 (21%)
Strychnine-binding. {ECO:0000250|UniProtKB:O93430} 236..241 4/13 (31%)
NtRNP_651958.2 Methyltransf_FA 90..191 CDD:289052
Neur_chan_LBD 212..429 CDD:280998 48/229 (21%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 O PTHR18945
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
11.100

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