DRSC/TRiP Functional Genomics Resources

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Protein Alignment GLRA2 and GluClalpha

DIOPT Version :10

Sequence 1:NP_002054.1 Gene:GLRA2 / 2742 HGNCID:4327 Length:452 Species:Homo sapiens
Sequence 2:NP_001287408.1 Gene:GluClalpha / 42350 FlyBaseID:FBgn0024963 Length:463 Species:Drosophila melanogaster


Alignment Length:434 Identity:190/434 - (43%)
Similarity:257/434 - (59%) Gaps:41/434 - (9%)


- Green bases have known domain annotations that are detailed below.


Human    48 LDKLMGRTSGYDARIRPN----FKGPPVNVTCNIFINSFGSVTETTMDYRVNIFLRQQWNDSRLA 108
            ||:::| ...|||||||:    ..||.| |..|||:.|...:.:.||:|.|.:..|:||.|.||.
  Fly    37 LDQILG-AGKYDARIRPSGINGTDGPAV-VRVNIFVRSISKIDDVTMEYSVQLTFREQWTDERLK 99

Human   109 YSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCP 173
            :.:.......|..:..:.:|.|||||:|||..:||::...|..:||..||.||||||::|||:||
  Fly   100 FDDIQGRLKYLTLTEANRVWMPDLFFSNEKEGHFHNIIMPNVYIRIFPNGSVLYSIRISLTLACP 164

Human   174 MDLKNFPMDVQTCTMQLESFGYTMNDLIFEWLSDGPVQVAEGLTLPQFILKEEKEL-GYCTKHYN 237
            |:||.:|:|.|.|::::.|:|:|.|||:|.|....||||.:.|.||:|.|  ||.| .||....|
  Fly   165 MNLKLYPLDRQICSLRMASYGWTTNDLVFLWKEGDPVQVVKNLHLPRFTL--EKFLTDYCNSKTN 227

Human   238 TGKFTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQSS 302
            ||:::|::|....:|:..|||||:|||..::||:||||||::..|.||||:||:||:|||.||:|
  Fly   228 TGEYSCLKVDLLFKREFSYYLIQIYIPCCMLVIVSWVSFWLDQGAVPARVSLGVTTLLTMATQTS 292

Human   303 GSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAAVNFVSR-------QHKEFLRLRRRQKRQNK 360
            |..||||.|||.||||:|..|||.|||.||||:|.||:.||       .|||.::.:||...|..
  Fly   293 GINASLPPVSYTKAIDVWTGVCLTFVFGALLEFALVNYASRSGSNKANMHKENMKKKRRDLEQAS 357

Human   361 EE------DVTRESRFNF-SGYGMGHCLQVKDGTAVKATPANPLP-----------QPPKDGDAI 407
            .:      |....:.|.. |.:..|...|    ..:...|.:||.           |.||..:..
  Fly   358 LDAASDLLDTDSNATFAMASQFARGGGQQ----KPLVRHPGDPLALEKRLQCEVHMQAPKRPNCC 418

Human   408 K---KKFVDRAKRIDTISRAAFPLAFLIFNIFYWITYKIIRHED 448
            |   .||..|:||||.|||..|||.|.:||:.||.||.....||
  Fly   419 KTWLSKFPTRSKRIDVISRITFPLVFALFNLVYWSTYLFREEED 462

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
GLRA2NP_002054.1 LIC 46..441 CDD:273305 186/425 (44%)
GluClalphaNP_001287408.1 LIC 3..455 CDD:273305 186/425 (44%)

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