Protein Alignment X11L and apba3

DIOPT Version :10

• Sequence 1: NP_001285376.1
• Gene: X11L / 252671
• FlyBaseID: FBgn0026313
• Length: 1170
• Species: Drosophila melanogaster
• Sequence 2: XP_002941438.2
• Gene: apba3 / 100495034
• XenbaseID: XB-GENE-995533
• Length: 630
• Species: Xenopus tropicalis
• Alignment Length: 753
• Identity: 263/753 - (34%)
• Similarity: 382/753 - (50%)
• Gaps: 171/753 - (22%)

  Fly   462 SQSQPV---HEHNGNGERLE----NDYNVMSASLATLTTDASQSALISDFASLPMPPAPPPSSPP 519
            :||.||   |.......:::    ..|...|.|.:..::.:.:..:..|         |...:||
 Frog     5 AQSPPVSSCHMRTQTPSQIDMETPQQYEECSVSCSLHSSQSLEDPVCMD---------PTDRAPP 60

  Fly   520 QIEIADASESMTMVPDADN--PLDSHYGAVYAAALGGTHTEKSAGSGLGVTP----VTAGGSLPS 578
            :::         ..||.|.  ||                           ||    :...|.:|.
 Frog    61 RVD---------SCPDMDTRPPL---------------------------TPELNVMDLDGDVPG 89

  Fly   579 QAASEIQEAMKE---------IRSALQRAKTQPEKLKFCDEVLPTD---------PDSPVWVPRK 625
            : ...:||.:.|         :|.:|.......:.|:...|..|..         .:.|..|...
 Frog    90 E-GFHMQELLNELTTLEEPLDVRPSLNNLNEATDNLEGQAEGQPCPLHIAMGKGLSEKPRRVSES 153

  Fly   626 GTTISTAQGAAADEEPDTDLETDRLLGQQRHDEQDFFAD----------QSLADNNANEGTDIAS 680
            .|.:|.::|...     ||..::.||...:| |:...||          :.|..|.::....:..
 Frog   154 ETMLSNSRGLFL-----TDAGSEELLHLFQH-EEGVLADVGSAVPLARLEELPKNKSSVSCSLQE 212

  Fly   681 NGHLNGTSDNNNPNPMNNSKPQTYSTATIRQGIGTSLTPNSPDICQIVGTTDISISSPEKLQFTK 745
            .|  .|:|:.     :....|.::|:                |:|:     :.|.||.|::.
 Frog   213 AG--KGSSEE-----VKQKSPSSFSS----------------DLCR-----EDSFSSLEEVP--- 246

  Fly   746 SPTGSIKSLKDSANSDKKAKSRNKEGLLEPKVLIEGVLFRARYLGSTQLVCEGQPTKSTRMMQAE 810
                ..::|...:.:...||   ..|..:|:.|.:||:|.|:|||||||..|..|..||||.||:
 Frog   247 ----DEETLDTPSETTSAAK---VPGPCDPEDLKDGVIFGAQYLGSTQLPGEKHPVASTRMRQAQ 304

  Fly   811 EAVSRIKALAPEGESQPSTEVDLFISTEKIMVLNTDLKEIMMDHALRTISYIADIGDLVVLMARR 875
            |||.|||  ||:|||||.||||:.:||.::.||:.|.:|.:|||.|.|||:.||||.:|||||||
 Frog   305 EAVDRIK--APDGESQPMTEVDIMVSTRRVKVLSADSQESLMDHPLHTISFTADIGSIVVLMARR 367

  Fly   876 RFVPNSVVDPSITSPLGDVPTPGIGEEESPPKEPLSKHNRTPKMICHVFESDEAQFIAQSIGQAF 940
            : :|.:                   :::||.:.   |.||   ::||||:||:||.|||:|||||
 Frog   368 K-IPRT-------------------QDQSPTQR---KPNR---ILCHVFQSDDAQLIAQAIGQAF 406

  Fly   941 QVAYMEFL---KANGIENESLAKEMDYQEVLNSQEIFGDELEIFAKKELQKEVVVPKAKGEILGV 1002
            .:||.:||   :...:.:.|..:|         :.::..:|..|:|.:..:||.:.|.:||:||:
 Frog   407 GLAYQKFLCSDRVGPLTSGSGQRE---------EHLYNADLPHFSKSDSCREVYIQKQRGEMLGI 462

  Fly  1003 VIVESGWGSMLPTVVIANLMSSGAAARCGQLNIGDQLIAINGMSLVGLPLSTCQSYIRNAKNQTA 1067
            .:|||||||:||||||||||..|.|.|.|.|:|||.:.::||.||||||.||||..||:.|.|:.
 Frog   463 AVVESGWGSLLPTVVIANLMHGGPAERSGDLSIGDHVTSVNGTSLVGLPFSTCQGLIRDLKGQSE 527

  Fly  1068 VKFTVVPCPPVVEVKILRPKALFQLGFSVQNGVICSLLRGGIAERGGVRVGHRIIEINNQSVVAV 1132
            |..::|.||||:...|.||....||||.|::||||||:|||||||||:||||||||||.|||||.
 Frog   528 VILSIVRCPPVITAIIQRPSVSHQLGFCVEDGVICSLVRGGIAERGGIRVGHRIIEINGQSVVAT 592

  Fly  1133 PHDTIVKLLSSSVGEILMKTMPTSMFRLLTGQETPIYI 1170
            .|:.|::.|..:.||:.:||||.|.:|||||||.|:|:
 Frog   593 AHEKIIQTLMDATGEVHIKTMPASTYRLLTGQEIPVYL 630

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
X11L	NP_001285376.1	PTB_X11	775..954	CDD:269919	88/181 (49%)
		PDZ1_APBA1_3-like	988..1071	CDD:467203	49/82 (60%)
		PDZ2_APBA1_3-like	1082..1154	CDD:467255	45/71 (63%)
apba3	XP_002941438.2	PTB_X11	269..414	CDD:269919	86/172 (50%)
		PDZ1_APBA1_3-like	448..533	CDD:467203	49/84 (58%)
		PDZ2_APBA1_3-like	537..614	CDD:467255	47/76 (62%)