Protein Alignment FUS and Fus

DIOPT Version :10

• Sequence 1: NP_004951.1
• Gene: FUS / 2521
• HGNCID: 4010
• Length: 526
• Species: Homo sapiens
• Sequence 2: NP_001012137.1
• Gene: Fus / 317385
• RGDID: 1308864
• Length: 518
• Species: Rattus norvegicus
• Alignment Length: 529
• Identity: 501/529 - (94%)
• Similarity: 504/529 - (95%)
• Gaps: 14/529 - (2%)

Human     1 MASNDYTQQATQSYGAYPTQPGQGYSQQSSQPYGQQSYSGYSQSTDTSGYGQSSY-SSYGQSQNT 64
            |||||||||||||||||||||||||||||:|||||||||||.||.|||||||||| |||||:|||
  Rat     1 MASNDYTQQATQSYGAYPTQPGQGYSQQSNQPYGQQSYSGYGQSADTSGYGQSSYGSSYGQTQNT 65

Human    65 GYGTQSTPQGYGSTGGYGSSQSSQSSYGQQSSYPGYGQQPAPSSTSGSYGSSSQSSSYGQPQSGS 129
            ||||||.|||||||||||||||||||||||||||||||||||||||||||.|||||||||||||.
  Rat    66 GYGTQSAPQGYGSTGGYGSSQSSQSSYGQQSSYPGYGQQPAPSSTSGSYGGSSQSSSYGQPQSGG 130

Human   130 YSQQPSYGGQQQSYGQQQ-SYNPPQGYGQQNQYNSSSGGGGGGGGGGNYGQDQSSMSSGGGSGGG 193
            |.||..|||||||||||| |||||||||||||||||| |||||||||||||||||| ||||.|||
  Rat   131 YGQQSGYGGQQQSYGQQQSSYNPPQGYGQQNQYNSSS-GGGGGGGGGNYGQDQSSM-SGGGGGGG 193

Human   194 YGNQDQSGGGGSG-GYGQQDRGGRGRGGSGGGGGGGGGGYNRSSGGYEPRGRGGGRGGRGGMGGS 257
            |||||||||||.| |.||||||||||        |||||||||||||||||||||||||||||||
  Rat   194 YGNQDQSGGGGGGYGGGQQDRGGRGR--------GGGGGYNRSSGGYEPRGRGGGRGGRGGMGGS 250

Human   258 DRGGFNKFGGPRDQGSRHDSEQDNSDNNTIFVQGLGENVTIESVADYFKQIGIIKTNKKTGQPMI 322
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Rat   251 DRGGFNKFGGPRDQGSRHDSEQDNSDNNTIFVQGLGENVTIESVADYFKQIGIIKTNKKTGQPMI 315

Human   323 NLYTDRETGKLKGEATVSFDDPPSAKAAIDWFDGKEFSGNPIKVSFATRRADFNRGGGNGRGGRG 387
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Rat   316 NLYTDRETGKLKGEATVSFDDPPSAKAAIDWFDGKEFSGNPIKVSFATRRADFNRGGGNGRGGRG 380

Human   388 RGGPMGRGGYGGGGSGGGGRGGFPSGGGGGGGQQRAGDWKCPNPTCENMNFSWRNECNQCKAPKP 452
            ||||||||||||||||||||||||||||||||||||||||||||||||||||||:||||||||||
  Rat   381 RGGPMGRGGYGGGGSGGGGRGGFPSGGGGGGGQQRAGDWKCPNPTCENMNFSWRSECNQCKAPKP 445

Human   453 DGPGGGPGGSHMGGNYGDDRRGGRGGYDRGGYRGRGGDRGGFRGGRGGGDRGGFGPGKMDSRGEH 517
            ||||||||||||||||||||| |||||||||||||||||||||||||||||||||||||||||||
  Rat   446 DGPGGGPGGSHMGGNYGDDRR-GRGGYDRGGYRGRGGDRGGFRGGRGGGDRGGFGPGKMDSRGEH 509

Human   518 RQDRRERPY 526
            |||||||||
  Rat   510 RQDRRERPY 518

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
FUS	NP_004951.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..286		261/287 (91%)
		RRM_FUS_TAF15	283..368	CDD:409951	84/84 (100%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	375..424		48/48 (100%)
		zf-RanBP	422..449	CDD:395516	25/26 (96%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	444..526		80/81 (99%)
Fus	NP_001012137.1	RRM_FUS_TAF15	276..361	CDD:409951	84/84 (100%)
		zf-RanBP	415..442	CDD:395516	25/26 (96%)