Protein Alignment Gclm and Akr1c21

DIOPT Version :10

• Sequence 1: NP_732780.1
• Gene: Gclm / 248194
• FlyBaseID: FBgn0046114
• Length: 285
• Species: Drosophila melanogaster
• Sequence 2: NP_084177.2
• Gene: Akr1c21 / 77337
• MGIID: 1924587
• Length: 323
• Species: Mus musculus
• Alignment Length: 271
• Identity: 55/271 - (20%)
• Similarity: 97/271 - (35%)
• Gaps: 68/271 - (25%)

  Fly     5 ITKKYQNVVISTGNII-----ATELGQRKSNEELYDGLKITL-----HTDSTAERVVVEKEIDEL 59
            :..|...|:::.||.|     .|.|.......:..:..||.:     |.||.:    |....|.:
Mouse     1 MNSKCHCVILNDGNFIPVLGFGTALPLECPKSKAKELTKIAIDAGFHHFDSAS----VYNTEDHV 61

  Fly    60 HGRVQRATQELTTRLTENGRNEISIGAKIFLNRHSTESVNQAVEELLHILSVTHVDNVVLAYHPN 124
            ...::....:.|.|     |.:|...:|::......|.|..::|..|..|...:|| :.|.::|.
Mouse    62 GEAIRSKIADGTVR-----REDIFYTSKVWCTSLHPELVRASLERSLQKLQFDYVD-LYLIHYPM 120

  Fly   125 AVATATPVATTKP-----PCSED-----SNVSRATNWSQRNGKEGVAELKELYKTLEQYALKQQI 179
            |:         ||     |..|.     ..|.....|      |.:.:.|:...|
Mouse   121 AL---------KPGEENFPVDEHGKLIFDRVDLCATW------EAMEKCKDAGLT---------- 160

  Fly   180 TQLGIADLDAAALEELHN--SAQVVPTIAQVNLSTCC---VVPPELQEFCTAHDIQLNTHSDPEL 239
            ..:|:::.:...||.:.|  ..:..|...||.    |   :...:|.:||.:.||.|..:.
Mouse   161 KSIGVSNFNYRQLEMILNKPGLKYKPVCNQVE----CHPYLNQMKLLDFCKSKDIVLVAYG---- 217

  Fly   240 LLPVEQFDGLV 250
            :|..:::.|.|
Mouse   218 VLGTQRYGGWV 228

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gclm	NP_732780.1	AKR_SF	<79..>235	CDD:444925	36/170 (21%)
Akr1c21	NP_084177.2	AKR_AKR1C1-35	6..308	CDD:381334	54/266 (20%)