Protein Alignment Gclm and Akr1c12l1

DIOPT Version :10

• Sequence 1: NP_732780.1
• Gene: Gclm / 248194
• FlyBaseID: FBgn0046114
• Length: 285
• Species: Drosophila melanogaster
• Sequence 2: NP_001129216.1
• Gene: Akr1c12l1 / 498790
• RGDID: 1559604
• Length: 323
• Species: Rattus norvegicus
• Alignment Length: 223
• Identity: 46/223 - (20%)
• Similarity: 86/223 - (38%)
• Gaps: 39/223 - (17%)

  Fly    17 GNIIATELGQRKSNEELYDGLKITLHTDSTAERVVVEKEIDE-LHGRVQRATQELTTRLTENGRN 80
            |..|..|:.:.||.|.::..:....|...||....:|:||.: :..:::....:         |.
  Rat    22 GTSIPNEVPKSKSLEAVHLAIDAGYHHIDTASAYQIEEEIGQAIQSKIKAGVVK---------RE 77

  Fly    81 EISIGAKIFLNRHSTESVNQAVEELLHILSVTHVDNVVLAYHPNAVATATPVATTKPPCSEDS-- 143
            ::.|..|::......|.|..|:|:.|..|.:.:.|..::.|         ||    |..|.|.
  Rat    78 DMFITTKLWCTCFRPELVKPALEKSLKNLQLDYADLYIMHY---------PV----PMKSGDKYL 129

  Fly   144 NVSRATNWSQRNGKEGVAELKELYKTLEQYALKQQITQLGIADLDAAALEELHN--SAQVVPTIA 206
            .|.....|..     ...:..:.::.||:......:..:|:::.:...||.|.|  ..:..|...
  Rat   130 PVDDKGKWLL-----DTVDFCDTWEMLEKCKDAGLVKSIGVSNFNHKQLERLLNKPGLKYKPVCN 189

  Fly   207 QVNLSTCC---VVPPELQEFCTAHDIQL 231
            ||.    |   :...:|.::|.:.||.|
  Rat   190 QVE----CHLYMNQSKLLDYCKSKDIVL 213

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gclm	NP_732780.1	AKR_SF	<79..>235	CDD:444925	34/160 (21%)
Akr1c12l1	NP_001129216.1	AKR_AKR1C1-35	6..308	CDD:381334	46/223 (21%)