Protein Alignment Gclm and akr1a1a

DIOPT Version :10

• Sequence 1: NP_732780.1
• Gene: Gclm / 248194
• FlyBaseID: FBgn0046114
• Length: 285
• Species: Drosophila melanogaster
• Sequence 2: NP_001003783.1
• Gene: akr1a1a / 445326
• ZFINID: ZDB-GENE-040808-44
• Length: 324
• Species: Danio rerio
• Alignment Length: 305
• Identity: 67/305 - (21%)
• Similarity: 118/305 - (38%)
• Gaps: 81/305 - (26%)

  Fly     1 MIPTITKKYQNVVISTGNIIAT-ELGQRKSNE-ELYDGLKITL-----HTDSTAERVVVEKEIDE 58
            |..|||       :|||..:.| .||..||.. ::...:...|     |.|..| ....|:|:.|
Zfish     1 MTATIT-------LSTGQRMPTVGLGTWKSAPGQVKQAVLAALDCGYRHIDCAA-AYSNEREVGE 57

  Fly    59 LHGRVQRATQELTTRLTEN---GRNEISIGAKIFLNRHSTESVNQAVEELLHILSVTHVDNVVLA 120
                      .||.||...   .|::|.:.:|::..:|..:.|.:|....|..|.::::| :.|.
Zfish    58 ----------ALTERLGPGKSLRRDDIFVTSKLWNTKHHPDDVEEACRRSLSDLRLSYLD-LYLI 111

  Fly   121 YHPNAVATATPVATTKP--PCSEDSNVSRATNWSQRNGKEGVAELKELYKTLEQYALKQQITQLG 183
            :.|.|......:....|  ....|....|.| |:            .:.|.::|...|    .:|
Zfish   112 HWPMAFGRGDELIPRHPDGTIQYDDTHYRDT-WA------------AMEKLVDQGLAK----AIG 159

  Fly   184 IADLDAAALEELHNSAQVVPTIAQVNLSTCC---VVPPELQEFCTAHDIQLNTHS---DPE---- 238
            :::.:|..::::.:.|:..|.:.||.    |   :|..||...|.:.::.:..:|   .|:
Zfish   160 LSNFNAKQIDDILSIAKHKPVVNQVE----CHPYLVQAELASHCWSRNLTVTAYSPLGSPDRPWV 220

  Fly   239 -----LLLPVEQFDGLVPGYT-------IDWTLRYQVHVRCRGVL 271
                 |||...:..|:...|.       |.|      |:: |||:
Zfish   221 TPGEALLLDDPRVVGIAKSYNKTPAQVIIRW------HIQ-RGVV 258

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gclm	NP_732780.1	AKR_SF	<79..>235	CDD:444925	31/160 (19%)
akr1a1a	NP_001003783.1	AKR_AKR1A1-4	7..311	CDD:381332	63/292 (22%)