Protein Alignment Gclm and Akr1c19

DIOPT Version :10

• Sequence 1: NP_732780.1
• Gene: Gclm / 248194
• FlyBaseID: FBgn0046114
• Length: 285
• Species: Drosophila melanogaster
• Sequence 2: NP_001094046.1
• Gene: Akr1c19 / 307096
• RGDID: 1562954
• Length: 323
• Species: Rattus norvegicus
• Alignment Length: 322
• Identity: 66/322 - (20%)
• Similarity: 114/322 - (35%)
• Gaps: 100/322 - (31%)

  Fly     5 ITKKYQNVVISTGNII-ATELGQRKSNEELYDGLKITLHTDSTAERVVVEKEIDELHGRVQRATQ 68
            ::.|.|.|.::.|:.| |...|..|                  .|.|...|.::.:|..|:...:
  Rat     1 MSSKQQLVKLNDGHFIPALGFGTYK------------------PEEVPENKPLEAIHLAVEAGFR 47

  Fly    69 ELTTRL---TEN---------------GRNEISIGAKIFLNRHSTESVNQAVEELLHILSVTHVD 115
            .:.|..   |||               .|.:|.|..|::...|..|.|..::|:.|..|.:.:||
  Rat    48 HIDTAYVYQTENHVGQAIKSKIAAGIVKREDIFITTKLWCTFHRPEMVLSSLEKSLKNLQLDYVD 112

  Fly   116 NVVLAYHPNAVATATPVATTKPPCSEDSNVSRATNWSQRNGKE--GVAELKELYKTLEQYALKQQ 178
            ..::.| |..:.:...:      ..||           .|||.  ...:|...::.:|:......
  Rat   113 LYIIHY-PMQMKSGEDM------FPED-----------ENGKTLFDTVDLCATWEAMEKCKDAGL 159

  Fly   179 ITQLGIADLDAAALEELHN--SAQVVPTIAQVNLSTCC---VVPPELQEFCTAHDIQLNTH---- 234
            ...:|:::.:...||::.|  ..:..|...||.    |   :...:|..:|.:.||.|..:
  Rat   160 AKSIGVSNFNRRQLEKILNKPGLKYKPVCNQVE----CHLYLNQSKLLNYCKSRDIVLVAYCALG 220

  Fly   235 ----------SDPELLL-PV--------EQFDGLVPGYTIDWTLRYQVHVRCRG-VLTAKGY 276
                      |.|.||. ||        ::....:       .||||:.   || |:.|:.|
  Rat   221 SQRPKRWVDPSSPVLLNDPVLCDVAKKHQRSSAQI-------ALRYQLQ---RGNVVLAQSY 272

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gclm	NP_732780.1	AKR_SF	<79..>235	CDD:444925	34/176 (19%)
Akr1c19	NP_001094046.1	AKR_AKR1C1-35	6..308	CDD:381334	65/317 (21%)