Protein Alignment Gclm and gcs2

DIOPT Version :10

• Sequence 1: NP_732780.1
• Gene: Gclm / 248194
• FlyBaseID: FBgn0046114
• Length: 285
• Species: Drosophila melanogaster
• Sequence 2: NP_588368.1
• Gene: gcs2 / 2539059
• PomBaseID: SPCC737.06C
• Length: 287
• Species: Schizosaccharomyces pombe
• Alignment Length: 307
• Identity: 70/307 - (22%)
• Similarity: 126/307 - (41%)
• Gaps: 60/307 - (19%)

  Fly     5 ITKKYQNVVISTGNIIAT------ELGQRKSNEEL---YDGLKITLHTDSTAERVVVEKEIDELH 60
            |..:.:::::.||::...      ...:.|||.||   .:.:|:|..|....|.  ::|.|..|
pombe     2 IQNEKKHLILYTGDVTKNLKSGIWNASRIKSNLELVKALENVKLTKFTGDGDEN--LKKNIKVL- 63

  Fly    61 GRVQRATQELTTRLTENGRNEISIGAKIFL-------NRHSTESVNQAVEELLHILSVTHVDNVV 118
            ..|....|:|     :..:.|..|..|:|.       .:...|:::|....|..:..:..|..:|
pombe    64 VPVNEKPQKL-----DGKQEEYEIIVKLFFLDGENIDIKKREETLSQVFYNLHMLFGIDFVSTLV 123

  Fly   119 LAYHPNAVATATPVATTKPPCSEDSNVSRATNWSQRNGKEGVAELK--------ELYKTLEQYAL 175
            :::         |..|.         :..:.|.|.....:.:.|:.        :.:|.||:...
pombe   124 VSF---------PHITF---------LKESGNSSSNEIYDSIDEIPPQEIQSWVDTWKLLEEKVG 170

  Fly   176 KQQITQLGIADLDAAALEELHNSAQVVPTIAQVNLSTCCVVPPELQEFCTAHDIQLNTHSDPELL 240
            :.:|..||:::.....|:.|.:|..|||...|:|:...|.:|.:|..|...|.::|..||||..|
pombe   171 EGKIGTLGVSEFGVNELQRLISSVNVVPESTQINIGQNCKLPNDLLNFADRHHLKLFFHSDPSAL 235

  Fly   241 LPVEQFDGLV---------PGYTIDWTLRYQVHVRCRGVLTAKGYIV 278
            |...:...::         |. .:||.:||.:..|...|:..|||||
pombe   236 LSESEITSVIHKACPEIPNPA-RVDWVIRYTILTRHTAVIHQKGYIV 281

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gclm	NP_732780.1	AKR_SF	<79..>235	CDD:444925	34/170 (20%)
gcs2	NP_588368.1	AKR_SF	<100..281	CDD:444925	46/199 (23%)