Protein Alignment Tcp1 and CCT1

DIOPT Version :10

• Sequence 1: NP_036802.1
• Gene: Tcp1 / 24818
• RGDID: 3832
• Length: 556
• Species: Rattus norvegicus
• Sequence 2: NP_524450.2
• Gene: CCT1 / 42649
• FlyBaseID: FBgn0003676
• Length: 557
• Species: Drosophila melanogaster
• Alignment Length: 555
• Identity: 406/555 - (73%)
• Similarity: 475/555 - (85%)
• Gaps: 2/555 - (0%)

  Rat     1 MEGPLSVFGDRSTGEAIRSQNVMAAASIANIVKSSLGPVGLDKMLVDDIGDVTITNDGATILKLL 65
            :..|||:.|.|.:|.::|:||||||.||:||||||||||||||||||||||||:||||||||:||
  Fly     4 LASPLSIAGTRQSGASVRTQNVMAALSISNIVKSSLGPVGLDKMLVDDIGDVTVTNDGATILRLL 68

  Rat    66 EVEHPAAKVLCELADLQDKEVGDGTTSVVIIAAELLKNADELVKQKIHPTSVISGYRLACKEAVR 130
            ||||||||||.|||.|||:|||||||||||:||||||||||||||||||||:|||||:|||||.:
  Fly    69 EVEHPAAKVLVELAQLQDEEVGDGTTSVVILAAELLKNADELVKQKIHPTSIISGYRIACKEACK 133

  Rat   131 YINENLIINTDELGRDCLINAAKTSMSSKIIGINGDFFANMVVDAVLAVKYTDIRGQPRYPVNSV 195
            ||:|:|....||||||.|||.|||||||||||.:.:||:.|||||..:||.||.|||..|.:.::
  Fly   134 YISEHLTAPVDELGRDSLINIAKTSMSSKIIGADAEFFSAMVVDAAQSVKITDPRGQAAYSIKAI 198

  Rat   196 NILKAHGRSQIESMLINGYALNCVVGSQGMLKRIVNAKIACLDFSLQKTKMKLGVQVVITDPEKL 260
            |:|||||:|..||:||.||||||.:.||.|.|:|||||||||||||||||||:||||:|.||:||
  Fly   199 NVLKAHGKSARESVLIPGYALNCTIASQQMPKKIVNAKIACLDFSLQKTKMKMGVQVLINDPDKL 263

  Rat   261 DQIRQRESDITKERIQKILATGANVILTTGGIDDMCLKYFVEAGAMAVRRVLKRDLKRIAKASGA 325
            :.||.||.|||||||..||.||.||:|.:||:||:|:||||||||||||||.|.|||.||||:||
  Fly   264 EAIRARELDITKERINMILGTGVNVVLVSGGVDDLCMKYFVEAGAMAVRRVKKSDLKIIAKATGA 328

  Rat   326 SILSTLANLEGEETFEATMLGQAEEVVQERICDDELILIKNTKARTSASIILRGANDFMCDEMER 390
            :.:::|.|::|||:|:|:|:|:|.||.|||||||||||||.||||.:|||||||.|||.||||||
  Fly   329 AFITSLTNMDGEESFDASMVGEAAEVAQERICDDELILIKGTKARAAASIILRGPNDFYCDEMER 393

  Rat   391 SLHDALCVVKRVLESKSVVPGGGAVEAALSIYLENYATSMGSREQLAIAEFARSLLVIPNTLAVN 455
            |:||||||||||||||.||.|||.|||||||||||:|||:.|||||||||||:||||||.||:||
  Fly   394 SVHDALCVVKRVLESKKVVAGGGCVEAALSIYLENFATSLASREQLAIAEFAKSLLVIPKTLSVN 458

  Rat   456 AAQDSTDLVAKLRAFHNEAQVNPERKNLKWIGLDLVHGKPRDNKQAGVFEPTIVKVKSLKFATEA 520
            ||:|:||||||||::||.:|..|||.:|||.||||:.|..||||:|||.||.:.|:|||||||||
  Fly   459 AAKDATDLVAKLRSYHNSSQTKPERSDLKWTGLDLIEGVVRDNKKAGVLEPAMSKIKSLKFATEA 523

  Rat   521 AITILRIDDLIKLHPESKDDKHGGYENAVHSGALD 555
            |||||||||:|||:||.|..|  .|.:|..:|.||
  Fly   524 AITILRIDDMIKLNPEDKSGK--SYADACAAGELD 556

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tcp1	NP_036802.1	TCP1_alpha	9..535	CDD:239451	394/525 (75%)
CCT1	NP_524450.2	TCP1_alpha	12..538	CDD:239451	394/525 (75%)