DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG46385 and tent5aa

DIOPT Version :9

Sequence 1:	NP_001356959.1	Gene:	CG46385 / 246653	FlyBaseID:	FBgn0286778	Length:	1107	Species:	Drosophila melanogaster
Sequence 2:	XP_005157917.1	Gene:	tent5aa / 100330676	ZFINID:	ZDB-GENE-140106-27	Length:	393	Species:	Danio rerio

Alignment Length:	347	Identity:	201/347 - (57%)
Similarity:	253/347 - (72%)	Gaps:	13/347 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly   390 DTGG-TQRLAVLSFEQVSKLHDVMDEKVAIHGRGNFPTLEVKLKDLVNLVRRKLEAEVNAGGAGV 453
            |.|. :...:|||:|||.:|..::.|.:.||||||||||::|.:.:|..|||::..:      .:
Zfish     5 DAGAESSNFSVLSWEQVQRLDLILTETIPIHGRGNFPTLQMKPRQIVTAVRRRMREK------SI 63

  Fly   454 LVKDIRLNGGAASHVLASED-QPYNDLDLIFAIELSSPRVFDRVKVAVLNTLLDLMPEGVCKRRI 517
            .|:|:||||.||||||..:. ..|.||||||.:||.....|..||..||:.|||.:|:||.|.:|
Zfish    64 HVRDVRLNGSAASHVLHGDSGLGYKDLDLIFRVELKGETEFQIVKNIVLDCLLDFLPDGVNKEKI 128

  Fly   518 YTCSLKEAYVGKMVKVNNNNDGDRWSLISLGNSPGHKNVELKFVDTMRRQFEFSVDSFQIVLDSL 582
            ...:||||||.|||||  .||.||||||||.|:.| |||||||||::|||||||||||||.||||
Zfish   129 TPLTLKEAYVQKMVKV--CNDSDRWSLISLSNNRG-KNVELKFVDSLRRQFEFSVDSFQIKLDSL 190

  Fly   583 LLFYDCAALPISENFYPTVVGESVYGDFQEALYHLQKKLISTRQPEEIRGGGLLKYCNLLVRNYK 647
            ||||:|:..|:::.|:||::||||||||..||.||:.|:|.||.|||||||||||||:||||.::
Zfish   191 LLFYECSENPMAKTFHPTIIGESVYGDFAAALDHLRNKIICTRNPEEIRGGGLLKYCHLLVRGFR 255

  Fly   648 AVDSQLIKTLERYMCSRFFIDFPDINTQTTKLEAYLRNHFWGVDEEPLQYQYLMHLREVVEMSTV 712
            |.....:|:|:|||||||||||.||:.|..|||:||:|||.|:::.  :|.||..|..||..|||
Zfish   256 AASESEMKSLQRYMCSRFFIDFSDISEQQRKLESYLQNHFVGLEDR--KYDYLTTLHSVVNESTV 318

  Fly   713 CLMGHERRQSLHLIQSLAAQVL 734
            |||||||||:|.||..||.:||
Zfish   319 CLMGHERRQTLGLIAMLAVRVL 340

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG46385	NP_001356959.1	NTP_transf_7	400..727	CDD:311785	193/327 (59%)
tent5aa	XP_005157917.1	NTP_transf_7	16..334	CDD:285258	194/328 (59%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170573308
Domainoid	1	1.000	388	1.000	Domainoid score	I759
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000843
OrthoInspector	1	1.000	-	-		otm24679
orthoMCL	1	0.900	-	-		OOG6_104729
Panther	1	1.100	-	-	O	PTHR12974
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X528
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	8	7.840