Protein Alignment cGlr2 and MAB21L4

DIOPT Version :10

• Sequence 1: NP_001400984.1
• Gene: cGlr2 / 246606
• FlyBaseID: FBgn0050424
• Length: 459
• Species: Drosophila melanogaster
• Sequence 2: NP_001078906.3
• Gene: MAB21L4 / 79919
• HGNCID: 26216
• Length: 447
• Species: Homo sapiens
• Alignment Length: 226
• Identity: 47/226 - (20%)
• Similarity: 76/226 - (33%)
• Gaps: 58/226 - (25%)

  Fly   121 PREDFQRIRELIQG--------RLVDAQNFFVVDRLRSWLQSLFSQALNRISYRVELVAGVVSHL 177
            |....:||  |.||        :|......:::.||...|.||....|:.:|     :...|:|.
Human   224 PEGSLRRI--LSQGVDLVPASAQLWRTSTDYLLTRLLGELGSLQGHRLDSLS-----ILDRVNHE 281

  Fly   178 KYRTCGPAHTIYVYGDYEYSVDYVPAICLAAEQ----------------NVLPTKQLECFKRANT 226
            .:|..|....: .:|..:..:.:...:.||.|.                ..|.|::|..|..
Human   282 SWRDSGQTDGL-TFGHLKMVLLWASVLFLAPEDWAELQGAVYRLLVVLLCCLATRKLPHFLH--- 342

  Fly   227 SYWEAIPKPLKPLTETSMISFRSSFYAVEKILLQDVHENCRNAIRFMKKFRDVKTNLGNCKSYYI 291
                    |.:.|.:.|.:...:.:..||....|.     ..|:|..      .|:||......|
Human   343 --------PQRNLLQGSGLDLGAIYQRVEGFASQP-----EAALRIH------ATHLGRSPPPRI 388

  Fly   292 KTLFLWKIIQEPES---YWLNPLSFILADMF 319
            .: .|..::|.|.|   ||......:|.|.|
Human   389 GS-GLKALLQLPASDPTYWATAYFDVLLDKF 418

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cGlr2	NP_001400984.1	Mab-21	69..261	CDD:460873	31/163 (19%)
		Mab-21_C	265..359	CDD:466416	15/58 (26%)
MAB21L4	NP_001078906.3	Mab-21_C	<296..350	CDD:466416	9/64 (14%)