DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30424 and itprip

DIOPT Version :9

Sequence 1:	NP_001097455.1	Gene:	CG30424 / 246606	FlyBaseID:	FBgn0050424	Length:	389	Species:	Drosophila melanogaster
Sequence 2:	NP_001017872.1	Gene:	itprip / 550570	ZFINID:	ZDB-GENE-050417-422	Length:	539	Species:	Danio rerio

Alignment Length:	351	Identity:	72/351 - (20%)
Similarity:	125/351 - (35%)	Gaps:	109/351 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 KIAKPNEFDLV--FKLKFPYYKSIAVTRDP--KIP------GNVLL------------------- 38
            :::||...||:  |....|......:..||  :||      |.:.|
Zfish   188 RVSKPPTCDLIVPFSPPQPLRFQFELWCDPSTEIPLDLQGCGRIQLIKPGGNGTDCLCGSIDLGD 252

  Fly    39 DMTRVL------ELLKDDPREDFQRIRELIQGRLVDAQNFFVVDRLRSWLQSLFSQALNRISYRV 97
            ||..:|      |:|:||      .:.||:..|   ...:....::..|.|...|:|..:||::.
Zfish   253 DMLCLLHNRNECEVLEDD------ALPELLCAR---DTTYLSKGQIMRWFQISVSKAWGKISHKY 308

  Fly    98 ELVAGVVSHLKYRTCGPAHTIYVYGDYEYSVDYVPAICL------AAEQNVLPTKQLECFKRANT 156
            :.      .|.:|                ::|:..|:.:      ....|:.|..|.|     ||
Zfish   309 DF------ELAFR----------------NLDFPGALKIKFPSGKTVVLNLTPAVQFE-----NT 346

  Fly   157 SYWEAIPKPLKPLTETSMIS---FRSSFYAVEKILLQDV---------HENCRNAIRFMKKFRDV 209
            ..:.....|    ::||..|   ::.|....||.||:.:         |.:|...:.|:.|.:..
Zfish   347 DAYLISHFP----SDTSNSSDTHWQLSLSVYEKNLLKHLAKSLPTNSCHIHCLQIVAFLHKKQTT 407

  Fly   210 KTNLGNCKSYYIKTLFLWKIIQEPESYWLNP--LSFILADMFDDLAENLRRGVITFFWDPELNMI 272
            .|......:|:|||..|..::.:..:.| .|  |...|.|:...|.::|.          |..:.
Zfish   408 LTGRSAFCNYHIKTALLHLLLSKRPAMW-QPQNLDSRLRDLLSFLQQSLE----------EKKLY 461

  Fly   273 DALTRDQVWEMYLCVQRIPRDLRGAE 298
            .||..:....:.:.|   |:.:|.||
Zfish   462 HALVGNPRIPVEILV---PKIIRTAE 484

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30424	NP_001097455.1	Mab-21	1..289	CDD:281298	68/340 (20%)
itprip	NP_001017872.1	CDC37_N	<25..61	CDD:296150
itprip	NP_001017872.1	Mab-21	<349..462	CDD:281298	27/127 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170582484
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.930