Protein Alignment cGlr2 and Itpripl2

DIOPT Version :10

• Sequence 1: NP_001400984.1
• Gene: cGlr2 / 246606
• FlyBaseID: FBgn0050424
• Length: 459
• Species: Drosophila melanogaster
• Sequence 2: NP_001028552.1
• Gene: Itpripl2 / 319622
• MGIID: 2442416
• Length: 535
• Species: Mus musculus
• Alignment Length: 363
• Identity: 73/363 - (20%)
• Similarity: 120/363 - (33%)
• Gaps: 98/363 - (26%)

  Fly    61 EFSLEGSVGDMLKIAKPNEFDLVFKLKFPYYKSIAVTRDPKIPGNVLLDMTRVLE-----LLKDD 120
            :|...||..:..||.:|:.||::..|:.|    ..|..:|:..|.. ..:|....     .||..
Mouse   155 DFIQVGSAYEQHKIRRPDSFDVLVPLRLP----PQVALEPRSLGTE-PSLTPAFRSCFVCALKAP 214

  Fly   121 PRED-------FQRIRELIQGRLVDAQ--NFFVVDRLRSWLQSLFSQALNRISY------RVELV 170
            |...       .:..:...:|..||.|  .......:..|.|:...::|..:.|      ||.|.
Mouse   215 PSPSGASTGQWHRDCKPFAEGFCVDVQGRRHLSATLVLRWFQAHLQRSLATVRYSLEGRCRVSLT 279

  Fly   171 AGVVSHLKYRTCGPAHTIYVYGDYEYSVDYVPAICLAAEQNVLPTKQLECFKRANTSYWEAIPKP 235
            .|.:.........|..|.|.......:|..:||:.|                 .:..:..|.|.|
Mouse   280 PGSLEQPPTLHILPCRTDYGCCRLSMAVRLIPAVHL-----------------GDGVFLVAPPPP 327

  Fly   236 LKP---LTETSMISFRSSFYAV-----EKILLQDVHENC------RNAIRFMKKFRDV------- 279
            ..|   |:|........:.:.|     |:.||..:.|..      ...::.:|..||:
Mouse   328 PSPSGALSELPGGLRAEALWGVNTARQEQKLLGWLQERAPPGACYLKCLQLLKALRDLGARGLDP 392

  Fly   280 --KTNLGN-CKSYYIKTLFLWKIIQE--PESYWLNPLSFILADMFDDLAENLRRGVITFFWDPEL 339
              .|:.|. ..||.:||..|..::.|  |...|...   .|::..:.|.:.||
Mouse   393 MAATHWGRILSSYVLKTAVLEVLLNEGSPTPSWDEA---HLSECLEKLVKFLR------------ 442

  Fly   340 NMIDALTRDQVWEMYLC----------VQRIPRDLRGA 367
               |.|.|.:  :::.|          |..:|:.||.|
Mouse   443 ---DCLLRRR--DLFHCVLGPTGAAAEVGPLPKVLREA 475

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cGlr2	NP_001400984.1	Mab-21	69..261	CDD:460873	43/219 (20%)
		Mab-21_C	265..359	CDD:466416	22/121 (18%)
Itpripl2	NP_001028552.1	Mab-21_C	374..496	CDD:466416	26/122 (21%)