Protein Alignment cGlr2 and cgas

DIOPT Version :10

• Sequence 1: NP_001400984.1
• Gene: cGlr2 / 246606
• FlyBaseID: FBgn0050424
• Length: 459
• Species: Drosophila melanogaster
• Sequence 2: XP_002937200.3
• Gene: cgas / 100488048
• XenbaseID: XB-GENE-6466735
• Length: 592
• Species: Xenopus tropicalis
• Alignment Length: 407
• Identity: 99/407 - (24%)
• Similarity: 150/407 - (36%)
• Gaps: 130/407 - (31%)

  Fly    42 SKIFEILRKENPELDIII----------AEFSLEGSVGDMLKIAKPNEFDLVFKLKFP------- 89
            ||..|.::|...:||..|          .|....||..:.:||:||||||::  ||.|
 Frog   257 SKAAEQVKKLVKDLDKFIKSSKDPAFEGMEILNTGSYYEKVKISKPNEFDIM--LKIPCGRLRIS 319

  Fly    90 -------YYKSIAVTRDPKIPGNVLLDMTRVLELLKDDPREDFQRIRELIQGRLVDAQNFFVVDR 147
                   :| ::.:.|:||.|      :|..:|..|...::...|:||||:.:|
 Frog   320 ESDASGSFY-TLTINRNPKHP------LTNYVENGKISGQQMLDRLRELIKSKL----------- 366

  Fly   148 LRSWLQSLFSQALNRISYRVELVAGVVSHLKYRTCGPAHTIYVYGDYEYSVDYVPAICLAAE-QN 211
                  |.....:|     ||         :.....||.||.:   .|.|||.|    ||.| :.
 Frog   367 ------SRLGTGIN-----VE---------RRNAASPAVTIKI---GEISVDLV----LALEVEG 404

  Fly   212 VLPTKQLECFK-------RANTSY-WEAIPKPLKPLTETSMISFRSSFYAVEKILLQDVHEN--- 265
            ..|:...|..|       :....| :|.:....|.|..|..|.:|.||..:||.:|:: |.|
 Frog   405 SWPSSTSEGMKIETWLGAKVKRDYKFEPMYFVAKQLKNTEEILWRISFSHIEKEILKN-HGNAKT 468

  Fly   266 ---------CR-NAIRFMKKFRDVKTNLGN------CKSYYIKTLFLWKIIQEPESYWLNPLSFI 314
                     || ..::.||...:...:.||      | ||:.||..|......|:.....|..
 Frog   469 CCETEGVKCCRKQCLKLMKYLLEQLKSKGNRNMTHFC-SYHAKTALLHSCTLYPKDDDWRPKD-- 530

  Fly   315 LADMFD----DLAENLRRGVITFFWDPELNMIDALTRDQVWEMYLCVQRIPRDLRGAEISRNKWS 375
            ||..||    |..:.|:...:..|:.|.||:...             :.||:          |..
 Frog   531 LAACFDRYIEDFMKCLKDARLPNFFIPSLNLFSE-------------ELIPK----------KCL 572

  Fly   376 FFVLREFSHKKERNVNL 392
            .::||:...:|:....|
 Frog   573 DYLLRKLDKQKKLQYTL 589

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cGlr2	NP_001400984.1	Mab-21	69..261	CDD:460873	56/214 (26%)
		Mab-21_C	265..359	CDD:466416	25/116 (22%)
cgas	XP_002937200.3	Mab-21	293..462	CDD:460873	56/215 (26%)
		Mab-21_C	478..581	CDD:466416	29/128 (23%)