DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30392 and Plekha3

DIOPT Version :9

Sequence 1:	NP_001286672.1	Gene:	CG30392 / 246587	FlyBaseID:	FBgn0050392	Length:	223	Species:	Drosophila melanogaster
Sequence 2:	NP_112546.1	Gene:	Plekha3 / 83435	MGIID:	1932515	Length:	297	Species:	Mus musculus

Alignment Length:	156	Identity:	32/156 - (20%)
Similarity:	58/156 - (37%)	Gaps:	33/156 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    81 AKDAEEQEHFNTFRT-MLDYEKEAQLLTQKGYVSGSRTLLRLHRGLDFVYEFLNRIQAIPDDQKT 144
            ||:.|..|...:.:| |.:......||.|:.:.               :.||::|.:..|  ..:
Mouse   101 AKEKEISETSESLKTKMSELRLYCDLLMQQVHT---------------IQEFVHRDERHP--SPS 148

  Fly   145 VDVCKEAYDDTLGKHHSFL--IRKGARLA-------MYAMPTRGDLLKKVC-SDVEAAKENL--P 197
            |:...||........::|:  :.:..::|       |:.:|....|:..|. |.|:..|.:.  |
Mouse   149 VENMNEASSLLSATCNTFITTLEECVKIANAKFKPEMFQLPHPDPLVSPVSPSPVQMMKRSASHP 213

  Fly   198 SMLKHMRTNYDRTEDLYTLYDLHSLP 223
            ......|::....|....   ||.||
Mouse   214 GSCSSERSSCSIKEPASA---LHRLP 236

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30392	NP_001286672.1	GLTP	42..186	CDD:285880	21/114 (18%)
Plekha3	NP_112546.1	PH_FAPP1_FAPP2	1..100	CDD:269951
		Interaction with SACM1L. /evidence=ECO:0000250\|UniProtKB:Q9HB20	1..100
		Interaction with VAPA and VAPB. /evidence=ECO:0000250\|UniProtKB:Q9HB20	97..297		32/156 (21%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	198..297		11/42 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910