DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG30392 and Plekha8

DIOPT Version :9

Sequence 1:	NP_001286672.1	Gene:	CG30392 / 246587	FlyBaseID:	FBgn0050392	Length:	223	Species:	Drosophila melanogaster
Sequence 2:	NP_001157833.1	Gene:	Plekha8 / 231999	MGIID:	2681164	Length:	519	Species:	Mus musculus

Alignment Length:	210	Identity:	56/210 - (26%)
Similarity:	94/210 - (44%)	Gaps:	34/210 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    30 ETSLLDEDDVQLDAYLAAYEEIMKFFQLMG-SVFSFVSSDVRSKIDILYALRAKDAEEQEHFNTF 93
            :..||::..:..:|:||:...::.....:| :||:.|..|:...|.   .:..|....:|.|.|.
Mouse   321 DIELLEDSGIPTEAFLASCYAVVPVLDKLGPTVFAPVKMDLVGNIK---KVNQKYITNKEEFTTL 382

  Fly    94 RTMLDYEKEAQLLTQKGYVSGSRTLLRLHRGLDFVYEFLNRIQAIPDDQKTVDVCKEAYDDTLGK 158
            :.::.:|.||.:...:.  |.:..||.|.|||.|:..||..::....|.:|  ....||..||.:
Mouse   383 QKIVLHEVEADVAQVRN--SATEALLWLKRGLKFLKGFLTEVKNGEKDIQT--ALNNAYGKTLRQ 443

  Fly   159 HHSFLIRKGARLAMYAMPT-----------RGDLLKKVCSDVEAAKEN-----LPSMLKHMRTNY 207
            ||.:::|....||:.|.|:           .||..|:..|   |..:.     ||:|.|.:..
Mouse   444 HHGWVVRGVFALALRAAPSYEDFVAALTIKEGDHQKEAFS---AGMQRDLSLYLPAMEKQLAI-- 503

  Fly   208 DRTEDLYTLYDLHSL 222
                 |.|||::|.|
Mouse   504 -----LDTLYEIHGL 513

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30392	NP_001286672.1	GLTP	42..186	CDD:285880	42/155 (27%)
Plekha8	NP_001157833.1	PH_FAPP1_FAPP2	1..100	CDD:269951
		PH	1..93	CDD:278594
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	275..302
		Glycolipid transfer protein homology domain	330..473		39/149 (26%)
		GLTP	333..470	CDD:285880	39/143 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910