Protein Alignment CG30340 and Prlhr

DIOPT Version :10

• Sequence 1: NP_724812.2
• Gene: CG30340 / 246550
• FlyBaseID: FBgn0050340
• Length: 396
• Species: Drosophila melanogaster
• Sequence 2: NP_963909.2
• Gene: Prlhr / 226278
• MGIID: 2135956
• Length: 370
• Species: Mus musculus
• Alignment Length: 332
• Identity: 91/332 - (27%)
• Similarity: 147/332 - (44%)
• Gaps: 64/332 - (19%)

  Fly    24 LHKPNGEITWKICTFLPLIAFGLYGNFSMVYVIATNRSLRSPTNLIIANMAVADLLTLAICPAMF 88
            :|:..|.|   :..:..::..||.||..:|.|||..|.|.:.||.:|.|:|::|:|..|.|..:.
Mouse    56 VHQLKGLI---VMLYSIVVVVGLVGNCLLVLVIARVRRLHNVTNFLIGNLALSDVLMCAACVPLT 117

  Fly    89 MVNDFY-QNYQLGCVGCKLEGFLVVVFLITAVLNLSVVSYDRLTAIVLPMETRLTIRGVQIVVVC 152
            :...|. :.:..|...|.|..||..|.:..:|..|:.::.||...:|.|:..|:::|.....|:.
Mouse   118 LAYAFEPRGWVFGGGLCHLVFFLQPVTVYVSVFTLTTIALDRYVVLVHPLRRRISLRLSAYAVLG 182

  Fly   153 TWVSGILLASPLAFYRSYRVRVWKNFTERYCKENTSVLPKYW-------------YVLITILVWL 204
            .|....:||.|.|.: :|.|.: |......|:|       :|             .:|.|.|  |
Mouse   183 IWALSAVLALPAAVH-TYHVEL-KPHDVSLCEE-------FWGSQERQRQIYAWGLLLGTYL--L 236

  Fly   205 PLGIMLICYIAIFYKLDRYEKRVLSRENPLTVSY---------KRSVAKTLFIVVVVFAALRLPF 260
            ||..:|:.|:.:..||   ..||:    |.:|:.         :|.....|.:||||||...||.
Mouse   237 PLLAILLSYVRVSVKL---RNRVV----PGSVTQSQADWDRARRRRTFCLLVVVVVVFAVCWLPL 294

  Fly   261 TILVVLR-------EKY-FGEDVSVSSGMQLFWYISQYLMFLNAAVNPLIYGFNNENFRRAYYQ- 316
            .|..:||       :.| ||          |...:..:|...:|..||.||.:.:::||....:
Mouse   295 HIFNLLRDLDPRAIDPYAFG----------LVQLLCHWLAMSSACYNPFIYAWLHDSFREELRKM 349

  Fly   317 -ISWVRR 322
             :||.|:
Mouse   350 LLSWPRK 356

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG30340	NP_724812.2	7tmA_BNGR-A34-like	33..314	CDD:320131	85/311 (27%)
		TM helix 1	33..59	CDD:320131	8/25 (32%)
		TM helix 2	66..91	CDD:320131	9/24 (38%)
		TM helix 3	104..134	CDD:320131	9/29 (31%)
		TM helix 4	145..166	CDD:320131	5/20 (25%)
		TM helix 5	190..219	CDD:320131	9/41 (22%)
		TM helix 6	237..267	CDD:320131	11/38 (29%)
		TM helix 7	282..307	CDD:320131	7/24 (29%)
Prlhr	NP_963909.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..33
		7tmA_PrRP_R	61..346	CDD:320516	87/315 (28%)
		TM helix 1	62..88	CDD:320516	9/28 (32%)
		TM helix 2	95..120	CDD:320516	9/24 (38%)
		TM helix 3	134..164	CDD:320516	9/29 (31%)
		TM helix 4	175..196	CDD:320516	5/20 (25%)
		TM helix 5	222..251	CDD:320516	8/30 (27%)
		TM helix 6	271..301	CDD:320516	11/29 (38%)
		TM helix 7	314..339	CDD:320516	8/34 (24%)
		Required for interaction with GRIP1, GRIP2 and PICK1. /evidence=ECO:0000250	365..370