DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30340 and npr-6

DIOPT Version :9

Sequence 1:	NP_724812.2	Gene:	CG30340 / 246550	FlyBaseID:	FBgn0050340	Length:	396	Species:	Drosophila melanogaster
Sequence 2:	NP_509725.2	Gene:	npr-6 / 185623	WormBaseID:	WBGene00009619	Length:	402	Species:	Caenorhabditis elegans

Alignment Length:	333	Identity:	84/333 - (25%)
Similarity:	149/333 - (44%)	Gaps:	64/333 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    48 GNFSMVYVIATNRSLRSPTNLIIANMAVADLL----TLAICPAMFMVNDFYQNYQLGCVGCKL-E 107
            |||.:|||:.||:.:::.||:.|.|:||:|::    :|.:.|....:..:.....| |.|..| :
Worm    54 GNFLVVYVVMTNKRMQTITNIFITNLAVSDIMVNFTSLWLTPTYTSIGHWIFGGGL-CHGLPLFQ 117

  Fly   108 GFLVVVFLITAVLNLSVVSYDRLTAIV-----LPMETRLTIRGVQIVVVCTWVSGILLASPLAFY 167
            |  ..:|:.|  ..|:.::.||...||     :.:..|:::|.....:|..|:..:||.:|
Worm   118 G--TSIFIST--WTLTAIAIDRYIVIVHNSSNININDRMSMRSCLSFIVLIWLCSLLLVTP---- 174

  Fly   168 RSYRVRVWKNFTERYCK--------ENTSVLPKYWYVLITILVWLPLGIMLICYIAIFYKLDRYE 224
              |.:.:..|:....|.        .|......:..|::.:...||..::.|.||.|:..|:
Worm   175 --YAINMKLNYIHEPCDFLICSEDWSNAEFRSIFGIVVMILQFILPFVLIAISYIKIWLFLN--- 234

  Fly   225 KRVLSRENPLTVSYKRSVAKTLFIVVVVFAALRLPFTILVVLREKYFGEDVSVSSGMQ---LFWY 286
            .|....|....:..|:.:.:.|.::||:||....||.:|..||      |:.:.:.|:   .|.:
Worm   235 SRQSMTERKSDIKRKKRLLRMLIVMVVIFAICWFPFNLLNCLR------DLKLDNFMRGYFSFVF 293

  Fly   287 ISQYLMFLNA-AVNPLIYGFNNENFRRAYYQI---SWVRR-------------------WRDATQ 328
            :|.:||.:.| |.||::|.|.||.||..:.::   .:.||                   :|.|.:
Worm   294 LSVHLMSMTATAWNPILYAFMNETFREEFAKVVPCLFARRPGTGPIRVITERTAMITNPFRRANR 358

  Fly   329 MKKFSRSP 336
            .||....|
Worm   359 KKKVEEQP 366

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30340	NP_724812.2	7tm_4	44..315	CDD:304433	77/288 (27%)
CG30340	NP_724812.2	7tm_1	48..303	CDD:278431	71/276 (26%)
npr-6	NP_509725.2	7tmA_NPYR-like	39..322	CDD:320331	77/287 (27%)
		TM helix 1	40..64	CDD:320331	6/9 (67%)
		TM helix 2	73..95	CDD:320331	7/21 (33%)
		TM helix 3	111..133	CDD:320331	6/25 (24%)
		TM helix 4	159..175	CDD:320331	5/21 (24%)
		TM helix 5	204..227	CDD:320331	4/22 (18%)
		TM helix 6	250..275	CDD:320331	8/24 (33%)
		TM helix 7	290..315	CDD:320331	10/24 (42%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910