DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30340 and npy2r

DIOPT Version :9

Sequence 1:	NP_724812.2	Gene:	CG30340 / 246550	FlyBaseID:	FBgn0050340	Length:	396	Species:	Drosophila melanogaster
Sequence 2:	XP_001343301.3	Gene:	npy2r / 100003852	ZFINID:	ZDB-GENE-040924-8	Length:	379	Species:	Danio rerio

Alignment Length:	370	Identity:	101/370 - (27%)
Similarity:	160/370 - (43%)	Gaps:	80/370 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    35 ICTFLPLIAFGLYGNFSMVYVIATNRSLRSPTNLIIANMAVADLLTLAICPAMFMVNDFYQNYQL 99
            |..:..:|.||:.||..::||:...|:|.:.||..|.|:||||||...:|....::...|..::.
Zfish    54 ILAYSTIIFFGMTGNSLVIYVVYKFRNLHTVTNYFIVNLAVADLLVNTLCLPFTLMYTLYGEWKF 118

  Fly   100 GCVGCKL----EGFLVVVFLITAVLNLSVVSYDRLTAIVLPMETRLTIRGVQIVVVCTWVSGILL 160
            |.|.|.|    :|..|.|..||    |:|::.||..:||..|||:::.....:|:..|||:..:|
Zfish   119 GQVMCYLLPYAQGLAVHVSTIT----LNVIALDRYRSIVYHMETKMSKDMCVVVIAITWVASAIL 179

  Fly   161 ASPLAFYRSYRV------RVWKNFTERYCKENTSVLPKYWYVLITILVWLPLGIMLICYIAIFYK 219
            |||||.:|.|..      :..:...|::...:|.. ..|...:..:...|||.|:...|..|:.|
Zfish   180 ASPLAIFREYVTFDLSPEQTIQGCAEKWPGSSTDG-TIYSIAMFFLQYGLPLSIISFAYTRIWNK 243

  Fly   220 L-----------DRYEKRVLSRENPLTVSYKRSVAKTLFIVVVVFAALRLPFTILVVLREKYFGE 273
            |           ||:::|             :...|.|..|||||....|||        ..|..
Zfish   244 LRNHVSPGGGRSDRHQRR-------------QKTTKMLVAVVVVFTVSWLPF--------HAFQL 287

  Fly   274 DVSVSSGM------QLFWYISQYLMFLNAAVNPLIYGFNNENFRRAYYQISWVRRWRDATQMKKF 332
            .|.:.|.:      :|.:.....:...:...||::||:.|.|:|.::..:              |
Zfish   288 AVDIDSSVLEMKDFKLLYTAFHIVAMCSTFANPILYGWMNRNYRGSFVAV--------------F 338

  Fly   333 SRSPDHCCYCAFMKNGKR---TSEAAQK--AGNLEKDISKDMSSA 372
            .        |..:.||.|   :|||.::  ..|||..||..::.|
Zfish   339 K--------CGRINNGMRRVSSSEAVREKCTRNLENTISIALTQA 375

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30340	NP_724812.2	7tm_4	44..315	CDD:304433	85/297 (29%)
CG30340	NP_724812.2	7tm_1	48..303	CDD:278431	78/281 (28%)
npy2r	XP_001343301.3	7tm_GPCRs	51..334	CDD:333717	87/305 (29%)
		TM helix 1	53..77	CDD:320095	8/22 (36%)
		TM helix 2	86..108	CDD:320095	10/21 (48%)
		TM helix 3	124..146	CDD:320095	8/25 (32%)
		TM helix 4	167..183	CDD:320095	7/15 (47%)
		TM helix 5	215..238	CDD:320095	5/22 (23%)
		TM helix 6	262..287	CDD:320095	11/32 (34%)
		TM helix 7	302..327	CDD:320095	5/24 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24235
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	2.010