Protein Alignment CG30338 and RWDD3

DIOPT Version :10

• Sequence 1: NP_724811.1
• Gene: CG30338 / 246548
• FlyBaseID: FBgn0050338
• Length: 288
• Species: Drosophila melanogaster
• Sequence 2: NP_056300.3
• Gene: RWDD3 / 25950
• HGNCID: 21393
• Length: 267
• Species: Homo sapiens
• Alignment Length: 249
• Identity: 60/249 - (24%)
• Similarity: 97/249 - (38%)
• Gaps: 66/249 - (26%)

  Fly    18 EELELLSSIYCAPGELHMLDAGVVADFNEFLKDDKTKP------ATSLLSHLEYVVKLTLPG--- 73
            |||.:|::|:|.|.|..:|... ..|...|....|.:.      ...|:.||.......|||
Human     7 EELSVLAAIFCRPHEWEVLSRS-ETDGTVFRIHTKAEGFMDVDIPLELVFHLPVNYPSCLPGISI 70

  Fly    74 -------KQCVEVRVELPHLYPLLEQARVSVHTTLLGKSKEQRLKNDLEQYHGERREEDAEPYIF 131
                   .|||.|:..      |||||.     :||                       :||.:.
Human    71 NSEQLTRAQCVTVKEN------LLEQAE-----SLL-----------------------SEPMVH 101

  Fly   132 QLLSWLQDRIEDLLKRPASEFEVQQVASSDPQQPPATELQRIWI---YSHHIKSSAKRQELIRQ- 192
            :|:.|:|..:..:|.:|.:....::...|    ...|....:||   :..|:::..|..:::.:
Human   102 ELVLWIQQNLRHILSQPETGSGSEKCTFS----TSTTMDDGLWITLLHLDHMRAKTKYVKIVEKW 162

  Fly   193 ARQLELTG-FSRPGKPGIICVEGDSANVQEFWRTIKALRWQKISVVRTEPRQRK 245
            |..|.||| ....||..:|.::||..|::|:      |..||.|.|..:...:|
Human   163 ASDLRLTGRLMFMGKIILILLQGDRNNLKEY------LILQKTSKVDVDSSGKK 210

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG30338	NP_724811.1	RWD_DRWD_ELF-like	22..145	CDD:480265	31/138 (22%)
		RWDD2_C	170..286	CDD:467814	22/81 (27%)
RWDD3	NP_056300.3	RWD_RWDD3	7..112	CDD:467655	34/139 (24%)
		Interaction with UBE2I/UBC9. /evidence=ECO:0000269|PubMed:25918163	13..15		0/1 (0%)
		Interaction with UBE2I/UBC9. /evidence=ECO:0000269|PubMed:25918163	100..102		0/1 (0%)
		RWDD3_C	139..247	CDD:467815	22/78 (28%)