DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment MFS1 and Slc17a3

DIOPT Version :9

Sequence 1:	NP_726254.1	Gene:	MFS1 / 246519	FlyBaseID:	FBgn0050272	Length:	497	Species:	Drosophila melanogaster
Sequence 2:	XP_006254003.1	Gene:	Slc17a3 / 266730	RGDID:	628815	Length:	538	Species:	Rattus norvegicus

Alignment Length:	467	Identity:	124/467 - (26%)
Similarity:	228/467 - (48%)	Gaps:	52/467 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 LLFLSIVVNY-MAKFNA--GVAVVAMTNAENTN-PN--------FPE------------------ 54
            :.|::.:.|: :...|:  .:.:|||.|  ||: |:        ||:
  Rat    81 IAFIAHICNFTLIAQNSIISITMVAMVN--NTDQPSHLNSSTEWFPDGLNGDQHEASKHLSIKAP 143

  Fly    55 -YDWNEMERSYILSSFFWGYILTQFMGGWLCRRYGARITMFVSTIGSALLVVLIPWCVSWGGWQA 118
             |:|:...:..|.||..:|.:|.|..||:|..:.|.:..:.::.:||:||.:.||...:.|  .|
  Rat   144 VYNWSPQTQGIIFSSVQYGMMLMQGPGGYLAGKLGTKKVVGIALLGSSLLTLCIPLAANLG--LA 206

  Fly   119 Y-CAIRMSMGLFQGFLFPCIHAHLANWCPVKERNRLGALANTGIDCGTLVAMFASGLLAASSIGW 182
            : .|.|...||.||..:....|....|.|..||:||.::|.:|:..|....:...|:: :.::||
  Rat   207 FLLATRAVQGLTQGAGYGGQFALWQKWAPPNERSRLCSIAMSGMILGIFAVLLVGGII-SEALGW 270

  Fly   183 PGIFYVSCGVGVLWCIVWWIFGANQPRESKFIGEAELNYIETSINSSRKAEEAELKATGPIPVPW 247
            |.:||:...:||:.|::|.|...:.|....:|...|..||.:|::....:||.        |:|.
  Rat   271 PFVFYIFGSIGVVCCLLWLILVYDDPVSHPWISSPEKEYILSSLDQQFNSEEQ--------PLPI 327

  Fly   248 KAIWTSVPFWALMVTRCCQSWGYSTLQTEMPAYMNGVLLMDMKSNALYSALPYLTSWVMAFVYLI 312
            ||:..|:|.|::.:......|..:||....|.|::.|..::::.|.|.|:||:..:||:..:..:
  Rat   328 KAMLKSLPLWSMCLCSMTHQWLVNTLIIYTPTYISSVFKVNIRDNGLLSSLPFFVAWVIGILGGL 392

  Fly   313 IADILLTRGIMSITGIRKSVNSIAFFVPAAALIGVSFLDNT--QKTLAVVLMCANVGINAGSTIG 375
            :||.||::....|| :||.:..:....|||.::.:.::.::  ..|..:.|.|   |::.....|
  Rat   393 LADFLLSKNFRLIT-VRKIITILGNTPPAALVVALPYVQSSYIATTTFLTLSC---GLSPLCQSG 453

  Fly   376 STINTIDLSPNHAGILMGIVNTASNIVPILTPLLVGIIVKDDHDREQWQIVFIISAVIFCVGNIV 440
            ..||.:|::|.:|.:|||.....::...::.|::.|..:..|.: ..|:..|.:...|...|.|:
  Rat   454 VYINALDIAPRYASLLMGTSRGLAHSSAVMVPIVAGFFLNQDSE-FGWRNFFFVLFAINLFGLII 517

  Fly   441 YVAFGKMVNQPW 452
            |:.|.|...|.|
  Rat   518 YLVFAKADIQEW 529

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
MFS1	NP_726254.1	MFS	18..444	CDD:119392	120/457 (26%)
MFS1	NP_726254.1	2A0114euk	19..456	CDD:129972	124/467 (27%)
Slc17a3	XP_006254003.1	2A0114euk	71..537	CDD:129972	124/467 (27%)
Slc17a3	XP_006254003.1	MFS	145..522	CDD:119392	108/392 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166342583
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2532
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D497052at2759
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.750